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J Med Oncl Ther 2017 | Volume 2 Issue 4
Oncology and Biomarkers Summit
November 27-28, 2017 | Atlanta, USA
Annual Congress on
Introduction:
Diabetes mellitus (DM) is a group of metabolic
diseases characterized by hyperglycemia resulting from
defects in insulin secretion, insulin action, or both. We
aimed to research association between serum HbA1C, lipid
profile, magnesium and blood glucose levels, hypothesizing
that early detection and treatment of lipid and magnesium
abnormalities can minimize the risk for cardiovascular
disorder and cerebrovascular accident in the type II diabetic
group.
Methodology:
Fasting blood glucose, HbA1C, TC, HDL, LDL,
VLDL, TG and magnesium levels were evaluated. Study
period from July 2016 to December 2016 among 60 patients
including male and females and divided into two groups. 30
patients study group with known history of Type II DM, who
attended the OPD of the Medicine Department of AVBRH
Hospital and 30 ages, sex matched healthy controls. The age
group between 30-40 years included in the study. Statistical
analysis was done by using descriptive and inferential
statistics and software used in the analysis was SPSS 17.0
version.
Results:
Results of serum lipid profile showed that the mean
values for TC, TG, HDL, LDL and VLDL in study group were
227.76±30.72, 152.23±40.94, 40.5±6.43, 153.30±27.70
and 33.00±9.94 mg/dl respectively and lipid profile
level is significantly higher in the cases as compared to
controls. Higher HbA1C level increases the risk for diabetic
complications. FBS showed significant positive correlation
with HBA1C (p<0.002). HDL has significant negative
correlation with HBA1C (p<0.008). Serum magnesium levels
were found low in study group as compared to controls.
Discussion/Conclusion:
Early detection in the abnormalities
of serum HbA1C, lipid profile and Mg can minimize the
risk for micro and macro angiopathies in the known type II
diabetic patients.
e:
sarmistha0035@gmail.comHbA1C, lipid profile and magnesium as a biomarker for early diagnosing type ii diabetes mellitus and its
associated complications in the rural region of Vidarbha, Maharashtra, India
Sarmistha Sarkar
Datta Meghe Institute of Medical Sciences, India