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Page 45

N o v e m b e r 0 5 - 0 6 , 2 0 1 8 | P h i l a d e l p h i a , U S A

3

rd

INTERNATIONAL OBESITY SUMMIT AND EXPO

&

&

DIABETES, NUTRITION, METABOLISM & MEDICARE

2

nd

International Conference on

Joint Event on

OF EXCELLENCE

IN INTERNATIONAL

MEETINGS

alliedacademies.com

YEARS

LASER, OPTICS AND PHOTONICS

World Conference on

Obesity Summit 2018 & Diabetes Conference 2018 & Laser Photonics Conference 2018

Biomedical Research

|

ISSN: 0976-1683

|

Volume 29

Ida Fidelis E Denosta et al., Biomed Res 2018, Volume 29 | DOI: 10.4066/biomedicalresearch-C7-019

MATERNAL RISK FACTORS ASSOCIATED

WITH RETINOPATHY OF PREMATURITY

AMONG PATIENTS IN EAST AVENUE

MEDICAL CENTER FROM 2010 TO 2015

Ida Fidelis E Denosta

and

Carina Cruz-Quimbo

East Avenue Medical Center, Philippines

Objectives:

This study aims to determine the maternal risk factors associated

with the development of retinopathy of prematurity (ROP).

Design:

A retrospective cohort study.

Setting:

The study was done in a tertiary government hospital.

Patients:

This study included admitted premature neonates in neonatal inten-

sive care unit (NICU) who underwent ROP screening. All patients with con-

genital abnormality of the eyes were excluded in the study.

Methodology:

List of admitted premature patients who underwent ROP

screening was collected within the study period. Demographic data was col-

lected from the patient’s medical records.

Statistical Analysis:

Descriptive statistics were presented for categorical out-

come measures. Wilcoxon rank sum test was used to compare two averages.

Chi-square test, Yates’ chi-square test and Fisher’s exact test were used to

compare proportions. Univariate and multivariate regression analyses were

used to estimate crude and adjusted odds-ratios, corresponding 95% CI and

based on p-value ≤ 0.05 statistical significance.

Result:

This study showed 57% cases of ROP, majority with Stage 1 (66%),

mostly female infants (53.4%; p<0.001), mildly asphyxiated (51.2%, p=0.290;

77.2%, p=0.117) and were small for gestational age (57.3%; p<0.001). On the

average, these infants underwent 1 day of either invasive or non-invasive me-

chanical ventilation, 2 days with FiO2 of >0.5 liters per minute, had two blood

transfusions, and with shorter hospital stay (17 vs 26 days; p<0.001). The

average age of mothers who delivered infants with ROP was 26 years old,

multipara (59.2%), and underwent normal spontaneous delivery (67%). About

half reported adequate prenatal check-ups (53.8%), and diagnosed with uri-

nary tract infection (40.1%).

Conclusion:

Data showed that mothers with urinary tract infection and pre-

eclampsia are more likely to deliver infants with retinopathy of prematurity

thus significant maternal risk factors of ROP.

Keywords:

Retinopathy of Prematurity, Neonates, Prematurity

Ida Fidelis E Denosta has completed her degree of bach-

elor of science major in psychology at the age of 20 in Far

Eastern University. She graduated as doctor of medicine

at Fatima University Medical Center. She completed her

residency training in pediatrics at east avenue medical

center last December 2016 as an assistant chief resi-

dent. She is an active member of the Philippine Medical

Association, Manila Medical Society and currently affiliat-

ed with Allied Care Experts (ACE) Medical Center-Quezon

City and Caloocan City North Medical Center (CCNMC)

as a junior consultant in the department of pediatrics.

idadenosta@yahoo.com

BIOGRAPHY