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N o v e m b e r 0 5 - 0 6 , 2 0 1 8 | P h i l a d e l p h i a , U S A
3
rd
INTERNATIONAL OBESITY SUMMIT AND EXPO
&
&
DIABETES, NUTRITION, METABOLISM & MEDICARE
2
nd
International Conference on
Joint Event on
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
alliedacademies.comYEARS
LASER, OPTICS AND PHOTONICS
World Conference on
Obesity Summit 2018 & Diabetes Conference 2018 & Laser Photonics Conference 2018
Biomedical Research
|
ISSN: 0976-1683
|
Volume 29
Ida Fidelis E Denosta et al., Biomed Res 2018, Volume 29 | DOI: 10.4066/biomedicalresearch-C7-019
MATERNAL RISK FACTORS ASSOCIATED
WITH RETINOPATHY OF PREMATURITY
AMONG PATIENTS IN EAST AVENUE
MEDICAL CENTER FROM 2010 TO 2015
Ida Fidelis E Denosta
and
Carina Cruz-Quimbo
East Avenue Medical Center, Philippines
Objectives:
This study aims to determine the maternal risk factors associated
with the development of retinopathy of prematurity (ROP).
Design:
A retrospective cohort study.
Setting:
The study was done in a tertiary government hospital.
Patients:
This study included admitted premature neonates in neonatal inten-
sive care unit (NICU) who underwent ROP screening. All patients with con-
genital abnormality of the eyes were excluded in the study.
Methodology:
List of admitted premature patients who underwent ROP
screening was collected within the study period. Demographic data was col-
lected from the patient’s medical records.
Statistical Analysis:
Descriptive statistics were presented for categorical out-
come measures. Wilcoxon rank sum test was used to compare two averages.
Chi-square test, Yates’ chi-square test and Fisher’s exact test were used to
compare proportions. Univariate and multivariate regression analyses were
used to estimate crude and adjusted odds-ratios, corresponding 95% CI and
based on p-value ≤ 0.05 statistical significance.
Result:
This study showed 57% cases of ROP, majority with Stage 1 (66%),
mostly female infants (53.4%; p<0.001), mildly asphyxiated (51.2%, p=0.290;
77.2%, p=0.117) and were small for gestational age (57.3%; p<0.001). On the
average, these infants underwent 1 day of either invasive or non-invasive me-
chanical ventilation, 2 days with FiO2 of >0.5 liters per minute, had two blood
transfusions, and with shorter hospital stay (17 vs 26 days; p<0.001). The
average age of mothers who delivered infants with ROP was 26 years old,
multipara (59.2%), and underwent normal spontaneous delivery (67%). About
half reported adequate prenatal check-ups (53.8%), and diagnosed with uri-
nary tract infection (40.1%).
Conclusion:
Data showed that mothers with urinary tract infection and pre-
eclampsia are more likely to deliver infants with retinopathy of prematurity
thus significant maternal risk factors of ROP.
Keywords:
Retinopathy of Prematurity, Neonates, Prematurity
Ida Fidelis E Denosta has completed her degree of bach-
elor of science major in psychology at the age of 20 in Far
Eastern University. She graduated as doctor of medicine
at Fatima University Medical Center. She completed her
residency training in pediatrics at east avenue medical
center last December 2016 as an assistant chief resi-
dent. She is an active member of the Philippine Medical
Association, Manila Medical Society and currently affiliat-
ed with Allied Care Experts (ACE) Medical Center-Quezon
City and Caloocan City North Medical Center (CCNMC)
as a junior consultant in the department of pediatrics.
idadenosta@yahoo.comBIOGRAPHY