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NEUROSCIENCE AND NEUROLOGICAL DISORDERS

PSYCHIATRY AND PSYCHOLOGICAL DISORDERS

&

International Conference on

International Conference on

J u n e 2 8 - 2 9 , 2 0 1 8 | D u b l i n , I r e l a n d

Journal of Neurology and Neurorehabilitation Research

|

Volume 3

Page 16

Note:

Joint Event on

D

epression is common among women and likely due to certain biological,

hormonal and social factors that are unique to women. Women are at higher

risk than men of developing depression particularly during the reproductive

years. The burden of depression is 50% higher for females than males. Mood

changes in women may be due to life events (divorce, death) or may be due

to hormones (pregnancy, menstrual cycle). MDD is the fourth common cause

of disability in female in all age groups. Life time prevalence is 10%-25% and

more common among married women. Late life depression is also common

in the elderly women. Dysthymia (Persistent Depressive Disorder) is common

in women. Bipolar disorder occurs with similar frequency in men and women

but Bipolar II significantly more common in female. Research suggests that

in women, hormones play a role in the development and severity of bipolar

disorder. Mixed mania and rapid cycling is more common in bipolar women.

Post-partum period is associated with high risk of onset and relapse of BD.

Premenstrual dysphoria is a heritable disorder. Genes related to estrogen and

serotonins are believed to be of primary importance in PMDD. In studies it has

been seen that centrally active progesterone metabolite allopregnanolone has

potential role in the pathogenesis of PMDD. Mood and anxiety disorders are

prevalent during pregnancy. Prenatal depression and Prenatal Bipolar Disorders

are common, and risk of recurrence of mania or depression needs proper

management. During the post-partum period about 85% of women experience

some mood disturbance and 10% to 15% of women experience clinically

significant symptoms. Post-partum depressions are of three categories: Post-

partum Blues, Non-psychotic major depression and Puerperal Psychosis.

Post-menopausal depression is also common and due to declining levels of

estrogen and progesterone. In PMD, vasomotor symptoms may be related to

the dysregulation of thermoregulatory center, associated with fluctuations

in estrogen levels and increased noradrenergic tone in hypothalamus.

Management of Depression in women is very important. Psychotherapy,

Cognitive Behavior Therapy plays a useful role. Different antidepressant drugs

are used considering safety, efficacy and tolerability. Mood stabilizers are used

for Bipolar Disorders, ECT is also used. Prevention of suicide needs special

attention.

Biography

Amarnath Mallik is a Consultant Psychiatrist

and he completed his practice from institutes

like Kothari Medical Centre, Kolkata, Woodlands

Hospital, Kolkata and Belle Vue Nursing home

Mumbai, India. He is a Specialist in the field of

Psychiatry and his expertise lies in the field of

Neuropsychiatry.

dramarnathmallik@gmail.com

DEPRESSION IN WOMEN

Amarnath Mallik

Woodlands Hospital, India

Amarnath Mallik, J Neurol Neurorehabil Res 2018, Volume 3