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May 16-17, 2019 | Prague, Czech Republic
2
nd
International Conference on
22
nd
International Conference on
Nanomaterials and Nanotechnology
Advanced Nanoscience and Nanotechnology
Joint Event
&
Journal of Materials Science and Nanotechnology | Volume 3
Mater Sci Nanotechnol, Volume 3
Nanodiamonds thermal probes for intracellular measurement of temperature
Martín Pedroza-Montero, F A Pedroza-Montero, K Santacruz-Gomez, M A Acosta-Elías, E Silva-campa, J A
Sarabia-Sainz, A Burgara-Estrella, A Angulo-Molina, B Castaneda, S Navarro-Espinoza
and
D Soto-Puebla
Universidad de Sonora, México
T
he use of nanodiamonds (ND) in medicine and biology
is based on their bio-compatibility in physiologic
environments and very low toxicity at the intracellular level.
In this regard, the precise measurement of temperature
in these environments allows the better knowledge of
biologic events, such as cell divisions and cell´s metabolisms
alterations. Both processes are important in the pathology of
cancer. A thermal nanoprobe made of ND is very plausible
because their magnetic, electric and optical properties have
a dependence on the temperature in the physiologic range
centred at 37.5
o
C. In this work, we present data on the
emission spectra of fluorescent nanodiamonds (FNDs), and
we study its behaviour when the temperature changes with a
phenomenological model. Here, the FNDs are in solution, and
the model included the contributions from the background
and spurious luminescent processes associated with
impurities or contamination. We obtained the thermometric
scales fromchanges of intensity, semi-width and shift position
related to Zero-Phonon Lines of N-V centre with low errors
and great precision. The incubation of FND solutions in
cellular culture provides the means for reading temperature
both
in situ
and in real time, which becomes a useful medical
tool for a complementary cancer diagnosis.
Speaker Biography
Martín Pedroza-Montero has completed his PhD from University of
Sonora, México and he cofunded three scientific groups devoted to
the study synthesis of nanovectors tissue specific, nanoplatforms
for bio spectroscopic cell studies and physics of cancer. He is the
former director (2014-2018) of Department for Research in Physics of
University of Sonora. He has published more than 50 papers in reputed
journals and has been serving as referee in specialized journal of
nanotechnology, nanoparticles, physics and medicine.
e:
martin.pedroza@unison.mx