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Journal of Biomedical Research | Volume: 29
November 19-20, 2018 | Paris, France
Molecular Biology, Tissue Science and Regenerative Medicine
International Conference on
Joint Event
&
4th World Heart Congress
AptaKan: An R package for the analysis of the data of fluorescent bioassays
N Phogat
Hochschule Furtwangen University, Germany
AptaKan is a contributed package to the statistical software R
and has a in-built Shiny app based Graphical User Interface
(GUI). It can be used to analyse data of gold nanoparticles and
ampicillin aptamer-based assays. The package is useful for:
1. Analysis of the data based on different statistical models;
2. Diagnostic plots of statistical models; 3. Computing the
concentration from fluorescent data with the help of different
statistical models; 4. Simulation of dissociation constant (Kd)
based on sigmoidal and non-sigmoidal models; 5. Analysing
the positivity (significance) of the assay statistically. Moreover,
a report of results can be downloaded dynamically using the
GUI, generated by applying R packages knitr and rmarkdown.
Finally, our package provides a template on handling R’s S4
classes in Shiny. The package can also be implemented on other
experimentaldatatoo,byarrangingthedatainspecifictemplate.
Speaker Biography
Navneet Phogat has done Master’s in Marine Biotechnology from Goa University, Goa,
India. During this time, he was awarded fellowship for two years from Department of
Biotechnology, Government of India. He has done Master’s in Biomedical Engineering
from Furtwangen University, Germany. Currently, he is pursuing his PhD from Tubingen
University, Tubingen, Germany. His research interests are in image processing, machine
learning, data science and artificial intelligence.
e:
N Phogat, Molecular Biology & Heart Congress 2018, Volume 29
DOI: 10.4066/biomedicalresearch-C8-022