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Allied J Med Res 2017
Volume 1 Issue 2
September 01-02, 2017 London, UK
3
rd
International Conference and Expo on
Herbal & Alternative Medicine
Herbal Medicine 2017
ALCAT® test and dysbiosis: A new insight
Aim:
The objective of the study was to evaluate
whether food intolerance is associated with an intestinal
dysbiosis.
Method:
77 patients (122 females, 54 males, 36.5
average age) positive for dysbiosis test were tested
by food intolerant test ALCAT®. Dysbiosis test is
considered positive when at least one of the parameters
considered (named INDICANO and SCATOLO,
both tryptophan metabolites) exceeds 10 μg/L (mild
dysbiosis). The dysbiosis diagnosis ranges used were:
between 10 and 20 μg/L (mild dysbiosis), between 20
and 40 μg/L (medium dysbiosis), greater than 40 μg/L
(severe dysbiosis). The ALCAT® test is an automated
cytotoxic test for intolerance that electronicallymeasures
volumetric shift in blood cells following incubation with
food antigens. The degree of reactivity was determined
by comparing a baseline distribution curve against the
distribution curve generated by the analysis of each
test agent/blood sample and by calculating the absolute
differences between curves and the standard deviation
(SD).
Results:
Patients with a mild dysbiosis, uniquely
determined by values between 10 and 20 µg/L of
the INDICANO parameter, exhibit higher degree of
reactivity compared to patients with a diagnosis of
severe dysbiosis (both parameters higher than 40 µg/L).
Conclusion:
This study provides evidence than in
the presence of a limited alteration of the intestinal
permeability, a reaction to food antigens (via ALCAT®
test diagnosis) can be more severe in patients with
greater intestinal permeability condition.
Biography
Pierluigi Pompei has completed his PharmD in 1988 at the University of Camerino
and his PhD degree in 1994, at the University of Ancona, Italy. He is currently
Associate Professor in the Unit of Pharmacology of the University of Camerino,
where he is Head of the Lab of Pharmacology and Sport Nutrition, and Head of the
County Marche for the SANIS (School of Sport Nutrition).
pete.pompei@unicam.itPierluigi Pompei
University of Camerino, Italy
Pierluigi Pompei, Allied J Med Res 2017