allied
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Allied J Med Res 2017
Volume 1 Issue 2
September 01-02, 2017 London, UK
3
rd
International Conference and Expo on
Herbal & Alternative Medicine
Herbal Medicine 2017
Oroma Nwanodi
Locum Tenens, USA
Oroma Nwanodi, Allied J Med Res 2017
Nutraceuticals:NongynecologicCancer
ChemoradiationSensitizers, Chemopreventives
andAdverse Effect Resolvers
N
utraceutical chemoradiation sensitization can
reduce conventional chemoradiation dosing, in
turn reducing conventional chemoradiation adverse
effects, while maintaining chemoradiation therapeutic
effectiveness. Nutraceuticals also prevent and treat
chemoradiation adverse effects from anxiety and
depression through xerostomia. Improved quality
of life motivates up to 75% of integrative oncology
users. Nutraceutical chemoprevention should
motivate everyone towards healthy diet consumption.
Diindolymethane and indole-3-carbinol can sensitize
pancreatic cancer to conventional chemotherapy.
Sulforaphane chemosensitizes arsenic trioxide,
doxorubicin, and gemcitabine. Turmeric is synergistic
with docetaxel in lung cancer treatment. Inositol
hexakisphosphate chemosensitizes for irinotecan
colon cancer therapy. Withaferin A is synergistic
with doxorubicin. Curcumin radiosensitizes prostate
cancer, polyunsaturated fatty acids radiosensitize
renal cancers, and sulforaphane radiosensitizes
head and neck cancers. Some Ferula species
derived monoterpenes independently reverse
multidrug resistance via p-glycoprotein inhibition.
Other Ferula species derived montoerpenes need
synergism with vinblastine to reverse multidrug
resistance. Fermented nutraceuticals may offer
additional micro-organism derived chemopreventive
properties. Diets can now be targeted against a
given type of cancer. Individual nutraceuticals
such as rice bran possess multiple encompassing
chemopreventive mechanisms of action: anti-
oxidation, anti-proliferation/pro-apoptosis, immune
modulation, and mucosal protection. Chemoradiation
sensitization equivalence, anti-angiogenesis, and
immune modulation are a few areas for future
research. Chemopreventive dietary research can
explore the quality of consumed products in addition
to component portions. Nutraceutical chemoradiation
sensitization has the potential to positively affect
most cancer patients.
Biography
Oroma Nwanodi graduated from Meharry Medical College of Nashville,
Tennessee in USA as a Medical Doctor in 2001. She specialized in Obstetrics
and Gynecology at The University of Massachussets and Maimonides Medical
Center. In 2013 and 2014, she obtained specialization in Integrative Holistic
Medicine. In 2016, she completed the Doctor of Health Science program at
A T Still University, Mesa, Arizona. She has practiced in California, Missouri,
Minnesota, and Wyoming. She has published more than 25 papers in reputed
journals and serves as an Editorial Board Member for several journals.
o.nwanodi@juno.com