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allied
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Asian Journal of Biomedical and Pharmaceutical Sciences | Volume 8
March 26-27, 2018 | Orlando, USA
World Summit on
Healthcare & Hospital Management
&
International Conference & Exhibition on
Biologics and Biosimilars
I
nfectious diseases possess a big challenge for the scientists
worldwide. Antibiotics were once a boon for mankind to
combat the infectious diseases. However, the emergence
of antibiotic resistance among superbugs is matter of great
concern throughout the world. Recent advances in the field of
nanotechnology particularly synthesis of metal nanoparticles of
specific size and shape are suggestive of bright future of these
materials. Nano-sized particles of the metal oxides viz. CuO and
ZnO were successfully synthesized using aqueous and alcoholic
extracts of
Swertia chirayita
as a reductant and stabilizer. The
as-prepared nanoparticles were further characterized by using
Fourier transform infrared spectroscopy, X-ray diffraction, UV-
visible spectroscopy, high-resolution transmission electron
microscopy, scanning electron microscopy and energy-dispersive
X-ray spectroscopy. These nanoparticles were evaluated for their
antibacterial efficacy against Gram-positive (
Staphylococcus
aureus
) as well as Gram-negative (
Escherichia coli
and
Salmonella
enterica
) bacterial strains. Among the two metal oxides, CuO
nanoparticles showed better antibacterial efficacy as compared
to ZnO nanoparticles against both the Gram-positive and Gram-
negative bacterial strains.
e:
faizmohammad54@rediffmail.comThe green synthesis and antibacterial efficacy of CuO and ZnO nanoparticles against Gram-positive
and Gram-negative bacteria
Mohammad F
Aligarh Muslim University, India