euro-green-chemistry-2019-scientifictracks

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May 22-23, 2019 | Rome, Italy

OF EXCELLENCE

IN INTERNATIONAL

MEETINGS

YEARS

Euro Green Chemistry 2019

Journal of Industrial and Environmental Chemistry | ISSN: 2591-7331 | Volume 3

CHEMISTRY AND

EURO GREEN CHEMISTRY

International Conference on

SYNTHESIS AND BIOLOGICAL EVALUATION OF NEW TRIAZOLE CONTAINING

CYPROHEPTADINE DERIVATIVES

Sandhya Jain, Drushti

and

Vikas Jain

ITM Universe, India

ental depression is a major affective disorder, common in the general population associated with deple-

tion of brain monoamines, 5-HT and NA. Anti-depressant therapy implies therapy directed against major

depressive disorder and is centred on the group of chemical agent: MAO-inhibitors; Monoamine reuptake in-

hibitors; Auto-receptor desensitizer and Antagonist. Earlier known the classes of the tricyclic anti-depressants

are termed as non-selective as they also interact with H1, α1 and muscarinic receptors to variable extent and

other one inhibit active uptake of biogenic amines NA and 5-HT into their respective neurons and thus poten-

tiate them. In author’s research work they select the cyproheptadine because it structurally resembles with

the TCA. The ring nitrogen is replaced with a carbon; the ethylamine chain is replaced by Methyl piperidine

replacement of basic group with neutral functionality preserves anti-histamine activity.

Sandhya Jain et al., J Ind Environ Chem 2019, Volume 3 | DOI: 10.4066/2591-7331-C2-011

Sandhya Jain is currently working in ITM School of Pharmacy as an Assistant Professor, Gujarat, India. She has eight years of experi-

ence in various fields. She worked in IPR division in Delhi especially in Patent Filing, Apart from this she is pursuing PhD and guiding

two students in post graduate level and more than ten students in bachelor degree. She has life time membership for APTI and she

is a Registered Pharmacist, during the Post-Graduation Degree she received the scholarship from AICTE, Delhi. She also did her MBA

and served as an Administrator in reputed organizations, with aim to provide better education to the student so they fulfils their

dream and make the world better place for humanity.

BIOGRAPHY