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May 22-23, 2019 | Rome, Italy
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alliedacademies.comYEARS
Euro Green Chemistry 2019
Journal of Industrial and Environmental Chemistry | ISSN: 2591-7331 | Volume 3
CHEMISTRY AND
EURO GREEN CHEMISTRY
9
th
International Conference on
SYNTHESIS OF FLUORESCENT TERNARY CORE-SHELL QUANTUM DOTS-PORPHYRIN
CONJUGATES AND ITS CELL VIABILITY AGAINST LEUKEMIA (THP-1) CANCER CELL
LINES
Oluwatobi S Oluwafemi
University of Johannesburg, South Africa
P
orphyrins are photosensitisers (PSs) used in Photo Dynamic Therapy (PDT) due to their tumor localisation
and
in situ
singlet oxygen generation. However, their limited absorption, insolubility and aggregation in
aqueous medium limited their effective application in PDT. In this presentation, a large scale aqueous synthesis
of CuInS2/ZnS core-shell, ternary quantum dots (QDs) and its conjugation to 5, 10, 15, 20-meso (4-hydroxyphe-
nyl) porphyrin as an efficient way to overcome photosensitizer shortcoming will be discussed. The singlet ox-
ygen generation of this highly aqueous soluble novel conjugate and its cell viability, which shows its potential
for PDT applications will also be discussed.
Oluwatobi S Oluwafemi, J Ind Environ Chem 2019, Volume 3 | DOI: 10.4066/2591-7331-C2-011
Oluwatobi S Oluwafemi is a National Research Foundation (NRF); South Africa rated researcher and a Full Professor at the Depart-
ment of Applied Chemistry, University of Johannesburg, South Africa. His research is in the broad area of nanotechnology and
include green synthesis of semiconductor and metal nanomaterials for different applications which include but not limited to bio-
logical (Imaging, labelling, therapeutic-PDT and PTT), optical, environmental and water treatment. He is the author and co-author of
many journal publications, book chapter and books. He is a reviewer for many international journals in the field of nanotechnology
and has won many accolades both national and international.
oluwafemi.oluwatobi@gmail.comBIOGRAPHY