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September 05-06, 2019 | London, UK
7
th
International Conference on
2
nd
International Conference on
Otolaryngology: ENT Surgery
Dental Health and Oral Hygiene
Joint Event
&
Chlorhexidine and bioglass can preserve the resin-dentine bonding
Ali A Alharbi
Alkharj Armed Forces Hospital, Saudi Arabia
D
espite all the improvements resin based dental
adhesive materials have gone through, leakage in
the resin-dentine interface is still a major limitation of
resin based dental restorative materials. Dentine matrix
metalloproteinases have been associated with this leakage
through their involvement in the proteolytic degradation
of the resin-dentine hybrid layer. The inhibitory effect of
chlorhexidine on this enzymatic activity is well established.
Bioactive glass materials can also reduce the resin-dentine
interface leakage through remineralisation of the dentine.
In this study RelyXTM Unicem AplicapTM was modified by
incorporatingchlorhexidineandBioglass45S5intothecement
composition. One hundred and fifty dentine specimens were
obtained from human permanent single rooted teeth and
restored with the test cements. The test cements push-out
bond strength was measured and statistically analysed after
ageing the specimens in artificial saliva for oneweek and after
nine months. The matrix metalloproteinases activity was
also quantified after each storage period. The study results
showed that incorporating chlorhexidine and Bioglass 45S5
jointly or separately into the composition of RelyXTMUnicem
AplicapTM did reduce MMP-2 activity after the short- and
long-term storage. It was also shown by the results of this
work that incorporating chlorhexidine and Bioglass 45S5
jointly, and chlorhexidine separately into the composition
of the cement also reduced MMP-9 activity after short- and
long-term storage.
Statistical analyses of the test results has shown that
incorporating chlorhexidine and Bioglass 45S5 into
the RelyXTM Unicem Aplicap TM cement composition
significantly preserves the push-out bond strength after up to
nine months of storage (p=0.02).
e
:
AliAlharbi@yahoo.comJ Clin Dentistry Oral Health
Volume: 3
Journal of Clinical Dentistry and Oral Health | Volume 3