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S e p t e m b e r 0 3 - 0 4 , 2 0 1 8 | B a n g k o k , T h a i l a n d
Note:
allied
academies
Joint Event on
Dental Congress 2018 & World Dermatology 2018
Archives of General Internal Medicine
|
ISSN: 2591-7951
|
Volume 2
WORLD DERMATOLOGY AND COSMETOLOGY CONGRESS
DENTISTRY AND ORAL HEALTH
&
International Conference on
F C Badea et al., Arch Gen Intern Med 2018, Volume 2 | DOI: 10.4066/2591-7951-C2-005
THE SUCCESS OF ORAL REHABILITATION
BY USING INTERLEUKINES TO MONITOR
PERI-IMPLANTITIS
F C Badea, A Caraiane , M Grigorian, C Nuca
and
V Badea
Ovidius University of Constanta, Romania
Introduction:
Interaction between bacterial species, host cells and biological
active factors, such as cytokines are currently considered as the basis in peri-
implantitis. Interleukin-1 (IL-1) and interleukin-6 (IL-6) are pro-inflammatory
cytokines present in crevicular fluid around dental implants (PICF), that can
play an important role in periodontal tissue destruction.
Aim:
The purpose of the present study was to compare the levels of IL-1
and IL-6 in PICF and to assess if there is a correlation between these two
interleukins and the orodental clinical status in peri-implantitis.
Methods:
The study group was composed of 14 subjects (eight males-57.2%
and six females-42.8% aged 30-45). Healthy implant (five subjects) was
considered if the implant had no bleeding on probing (BOP=0), probing depth
≤3 mm, normal gingival index (GI=0); peri-implantitis (nine subjects) was
considered when we identified bleeding on probing (BOP=1), probing depth ≥4
and gingival index (GI≥1). Clinical exam was performed in the Department of
Oral Rehabilitation, Faculty of Dental Medicine from Constanta; PICF samples
were collected and the quantitative determination of IL-1 and IL-6 was made
by using ELISA (Salimetrics, USA).
Results:
In our study we found that IL-1 and IL-6 levels were significantly
increased in peri-implantitis versus healthy implant; the results showed that
there are significant differences between IL-1 (p<0.001) and IL-6 (p=0.010)
mean values in the two groups of patients. There is also a high positive
correlation between probing depth and IL-1 (p=0.0008; r=0.904), IL-6 (p=0.02;
r=0.717) levels in peri-implantitis patients. Considering that only after
extensive demineralization the radiographs may be relevant to diagnosis and
based on our results, we appreciate that IL-1 and IL-6 can be used for peri-
implant tissues evaluation. The succes of the oral rehabilitation as a final goal
depends on the possibility of peri-implantitis evaluation using IL-1 and IL-6.
Conclusions:
Interleukin-1 and interleukin-6 can be used as biomarkers for
preventing, early diagnosis and correct monitoring of the peri-implantitis
patients.
F C Badea is a graduated, Faculty of Dental Medicine,
Ovidius University from Constantza, Romania, 2012.
In the same year he started the residency in Dental
Prostehtics wich he graduated in 2015. Between
2013-2017 he started and finished the PhD studies.
In 2013 he also become Assist.Prof., at the Faculty of
Dental Medicine, Ovidius University from Constantza,
Romania. He was passionate about research and it
materialised with articles published in different spe-
ciality literature and also presentation awardes at
different national and international congresses (APDC
second prize, Hong Kong).
florinb.md@gmail.comBIOGRAPHY