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June 12-13, 2019 | Edinburgh, Scotland
Pediatrics and Clinical Pediatrics
2nd World Congress on
Current Pediatric Research | Volume: 23
Celiac disease: Diagnostic dilemma
Bharat Parmar
Zydus Medical College, India
Celiac disease, an autoimmune disorders, occurs in
genetically susceptible individuals and is triggered by
the ingestion of a well-idenfined autoantigen- gluten. It
affects primarily the small intestine,where it progressively
leads to flattening of small intestinal mucosa. Three cereals
contain gluten and are toxic for Celiac patients – wheat,rye
and barley. It occurs more commonly in relatives of celiac
patients and some at risk groups. It causes gastrointestinal
symtoms, predominantly chronic diarrhoea with wastings,
but also many extra-intestinal menifestations can be
present alone. Suspected patient should be screened
with transglutaminase + total serum IgA and if positive,
confirmed by biopsy before the gluten-free diet is
started. A gluten free diet typically reverses all signs and
symptoms within a short time. Monitoring of the patient
to verify ongoing dietetic compliance is fundamental in
order to ensure that all possible complications, including
malignancies, are avoided.
Speaker Biography
Bharat Parmar has completedM.D (Paediatrics) FromGujarat University
Ahmedabad Gujarat India. He is working as a Professor and Head of
Paediatrics Department at ZYDUS Medical college Civil hospital. He has
completed 25 teaching experience in B.J Medical College Ahmedabad,
Gujarat India. He has published 15 research paper in national and
international journal. Recently one publication cited in Science Direct
and Pub Med. He has been serving as an editorial board member of
reputed Journal.
e:
Bharat Parmar, Current Pediatric Research, Volume 23
ISSN: 0971-9032