clinical-nutrition-2019-keynote

4 / 6

allied
academies
Page 12
Notes:
Journal of Nutrition and Human Health | Volume 3
November 21-22, 2019 | Singapore
Clinical Nutrition and Fitness
17th International Conference on
J Nutr Hum Health, Volume 3
Spasticity is a stiff muscle condition because the muscles
receive impulses continuously. Calcium ions play a role
in the ability of nerves to stimulate muscle contraction.
Spasticity occurs because of the continuous flow of Ca2+ into
the sarcomere which causes hyperexitation. This study aimed
to analyze the effect of calcium consumption on the changes
spasticity and the relation of calcium levels in the blood
and muscle to the spasticity. The experimental study was
conductedon42maleSprague-Dawley rats aged12-14weeks.
The 15-d intervention was conducted on six groups of spastic
rats by administering 20 g of feed containing 50 mg, 100 mg,
and 200 mg of calcium, it also received 100 mg, 200 mg, and
300mg of calcium lactate supplementation. The experimental
rats were induced with 80 mg/kg BW of Erythrocin B through
the tail vein to make them spastic. This study showed a
tendency of increased spasticity along with the increased
dose of calcium given to the subjects. There were significant
differences (p=0.007) in changes in spasticity between
groups. The significant differences (p=0.02) in changes in
blood calcium levels. The Spearman’s correlations test on
the changes in blood calcium levels and changes in spasticity
showed a positive coefficient correlation (r=0.097) with a
p-value of 0.54. An increase in blood calcium levels and a large
decrease in spasticity were found in the group receiving 100
mg calcium intake in 20 g of feed. The calcium levels inmuscles
had a significant correlationwith spasticity (p=0.038, r=0.810).
The calcium levels in themuscle had a strong. correlation with
blood calcium levels (p=0.041, r=0.748). The biggest decrease
in spasticity occurred after 100 mg of calcium were given to
the rats for 15 days, and it was considered as an optimal dose.
The calcium levels in the muscles had a strong correlation
with blood calcium levels and the spasticity of the spastic rat.
Speaker Biography
Marina Indriasari has completed her PhD at the age of 45 years fromBogor
Agricultural University, Bogor, West Java, Indonesia. She is the lecturer
of Faculty of Medicine and Health, Jakarta Muhammadiyah University,
Jakarta, Indonesia. She has 8 publications that one of them have been
viewed over 200 times and she has been serving as an editorial board
member of reputed Journals. She runs a therapy clinic independently
and practices as a physiatrist in a private hospital in Sukabumi, West Java ,
Indonesia. As her dedication to children with special needs, she consents
to the habilitation of children's growth and development. She has been
realizing the development of health services and children's growth and
development therapy. She builds an inclusion school for children with
special needs by establishing a friend's home foundation.
e:
Marina Indriasari
Bogor Agricultural University, Indonesia
Effect of calcium consumption on the spasticity in the spastic rat