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Journal of Nutrition and Human Health | Volume 3

November 21-22, 2019 | Singapore

Clinical Nutrition and Fitness

17

th

International Conference on

J Nutr Hum Health, Volume 3

E

vidence proved that gut microbiota plays a critical role in

human health and diseases. The host metabolic activities

and the composition of microbiota are closely associated

with host immune system that is linked to metabolic and

cognitive behaviour of the host. Probiotics are defined as live

microorganisms that exhibit health benefits on the host when

administered in adequate amounts. The possible mechanism

of health-promoting activities of probiotics is associated with

followings: positive alteration of gut-microbiota, secretion of

antagonistic substances, and neurotransmitters. The probiotic

and probiotic-based fermented foods are considered as a safe

and complementary therapeutic agent for the management

of metabolic disorders and cognitive declines. The recent

studies revealed that the probiotics improved the health

status of obese people by altering the gut microbiota, and

the regular consumption of probiotic is desirable to preserve

the health benefits. In the case of diabetes, the consumption

of probiotics may reduce the fasting blood glucose,

blood pressure, improved the lipid profile, glycaemic and

inflammatory status. The multi-strain probiotic formulations

exhibited positive results in most of the studies. Probiotic

supplementation improved the mood state, reduced

depression, stress, and anxiety, and reduced the severity of

the autism. Not all the probiotic supplementations provide

positive health benefits. It is purely based on the strain,

combinations, dosage, duration, supportive activities, and

host physiology. However, the safety, stability and shelf life of

probiotics product must be carefully studied to ensure their

beneficial impact on metabolic disorders and mental health.

Speaker Biography

ChaiyavatChaiyasut CisanassistantprofessorandthedirectorofInnovation

centerforholistichealth,nutraceuticalsandcosmeceuticalsattheFacultyof

Pharmacy, Chiang Mai University, Thailand. His research area is probiotics,

fermented foods, complementary, alternative and holistic therapeutic

approaches for metabolic disorders and brain function. He has over 110

publications that have been cited over 850+ times, and his publication

H-index is16andhasbeenservingasaneditorialboardmemberofreputed

Journals. He is the principal investigator for several research projects.

e:

chaiyavat@gmail.com

Chaiyavat Chaiyasut

Chiang Mai University, Thailand

Trend and evidence of probiotics as a complementary therapeutic

agent for metabolic disorders and brain function