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Chromatography 2018 & Satellite 2018
Journal of Chemical Technology and Applications
|
Volume 2
&
CHROMATOGRAPHY AND SEPARATION SCIENCE
World Congress on
SATELLITE AND SPACE MISSIONS
International Conference and Exhibition on
Joint Event on
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
alliedacademies.comYEARS
Satyajit Patra, J Chem Tech App 2018, Volume 2
APPLICATION OF ADVANCED
CHROMATOGRAPHY IN DISCOVERY OF
ANTICANCER DRUGS
I
dentification and quantification active biomolecules and metabolites includ-
ing secondary metabolites in a biological system is an integral part of the
system biology Metabolomics. Chromatography provides a platform to ana-
lyze the difference between metabolic unperturbed and perturbed networks,
one prominent example of use of chromatography in analyzing differences in
cancerous and non-cancerous samples. This offer detailed information of fun-
damentals of the disease pathology, disease prognosis and diagnosis. Many
researcher are focusing on identifying and analyzing metabolomics and its
extension of these information in the study of differential cancer cells, identi-
fication of novel drug molecules and biomarkers, however limited approaches
have been explored towards focusing a specific cancer cells or disease. The
answer to the long lasting questions of identification of suitable technology
for exploring these questions could be offered by Metabolomics to analyze
biomarkers, useful for identification and prediction of predisposition to cancer
and early stage diagnosis. In the field of cancer therapy this is very promising
and a important clinical need to eliminate severe pathological effect of cancer.
We will discuss use of metabolomics as a tool for analyzing biomarker and
discovery of novel drug molecule in cancer, and the principal focus will be on
the use of this tool to envisage resistance and sensitivity of anticancer drug,
and early diagnosis, prognosis, and metastasis of cancer.
Biography
Satyajit Patra is the Chairperson of Research and
PhD program at American International and Med-
ical University located at St. Lucia. He completed
M. Pharm in medicinal chemistry and PhD in Can-
cer molecular biology from Manipal University. He
obtained postdoctoral training in cancer genetics
from University of California San Diego, USA. He
has several peer reviewed publications that have
been cited over 200 times in different fields includ-
ing cancer, 3D bioprinitng, isolation of natural bio-
molecules.
dr.patra@aimu-edu.usSatyajit Patra
American International Medical University
USA