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N o v e m b e r 1 2 - 1 3 , 2 0 1 8 | R o m e , I t a l y

Note:

Page 32

Chromatography 2018 & Satellite 2018

Journal of Chemical Technology and Applications

|

Volume 2

&

CHROMATOGRAPHY AND SEPARATION SCIENCE

World Congress on

SATELLITE AND SPACE MISSIONS

International Conference and Exhibition on

Joint Event on

OF EXCELLENCE

IN INTERNATIONAL

MEETINGS

alliedacademies.com

YEARS

Satyajit Patra, J Chem Tech App 2018, Volume 2

APPLICATION OF ADVANCED

CHROMATOGRAPHY IN DISCOVERY OF

ANTICANCER DRUGS

I

dentification and quantification active biomolecules and metabolites includ-

ing secondary metabolites in a biological system is an integral part of the

system biology Metabolomics. Chromatography provides a platform to ana-

lyze the difference between metabolic unperturbed and perturbed networks,

one prominent example of use of chromatography in analyzing differences in

cancerous and non-cancerous samples. This offer detailed information of fun-

damentals of the disease pathology, disease prognosis and diagnosis. Many

researcher are focusing on identifying and analyzing metabolomics and its

extension of these information in the study of differential cancer cells, identi-

fication of novel drug molecules and biomarkers, however limited approaches

have been explored towards focusing a specific cancer cells or disease. The

answer to the long lasting questions of identification of suitable technology

for exploring these questions could be offered by Metabolomics to analyze

biomarkers, useful for identification and prediction of predisposition to cancer

and early stage diagnosis. In the field of cancer therapy this is very promising

and a important clinical need to eliminate severe pathological effect of cancer.

We will discuss use of metabolomics as a tool for analyzing biomarker and

discovery of novel drug molecule in cancer, and the principal focus will be on

the use of this tool to envisage resistance and sensitivity of anticancer drug,

and early diagnosis, prognosis, and metastasis of cancer.

Biography

Satyajit Patra is the Chairperson of Research and

PhD program at American International and Med-

ical University located at St. Lucia. He completed

M. Pharm in medicinal chemistry and PhD in Can-

cer molecular biology from Manipal University. He

obtained postdoctoral training in cancer genetics

from University of California San Diego, USA. He

has several peer reviewed publications that have

been cited over 200 times in different fields includ-

ing cancer, 3D bioprinitng, isolation of natural bio-

molecules.

dr.patra@aimu-edu.us

Satyajit Patra

American International Medical University

USA