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allied
academies
February 25-26, 2019 | Paris, France
13
th
World Cancer Congress
Journal of Medical Oncology and Therapeutics | Volume 4
Increased radiation dose and radiation related lifetime - Cancer risk in obese populations due to
Projection Radiography
Saeed J M Alqahtani
University of Exeter, United Kingdom
Purpose:
Primarily to evaluate the radiation dose delivered
to patients with obesity in projection radiography and its
relationship to the patient’s size. A secondary purpose is to
estimate the subsequent projected radiation-related lifetime
cancer risk to patients with obesity compared to normal-weight
patients.
Method and material:
Data from 1964 patients from a bariatric
clinic in the United Kingdom were reviewed with the relevant
permission. 630 patients were identified to have a projection
radiography history and were included in the study. Patients’
dose area product (DAP) data were collected for all projection
radiography. Multiple exams in one day including a single DAP
reading and exams with no records of DAP and exposure factors
were excluded. Correlations were calculated and data analysed
to yield the third quartile for each examination using STATA
14. Absorbed doses were generated from PCXMC simulation,
utilising DAP data from this study and the United Kingdom
national diagnostic reference level (NDRL), to calculate the
effective risk for patients with obesity compared to patients
with normal-weight.
Results:
Patients with obesity received higher DAPs for all
examinations included in this study compared to NDRL.
Abdominal and lumbar spine radiographsDAPswere thehighest
(17.6 and 30.31 Gy cm2) compared to the NDRL (2.5 and 4 Gy
cm2). Only moderate to low correlations were found between
patient’s size and DAPs in the abdomen and chest radiographs.
The projected radiation-related lifetime cancer risk for patients
with obesity is up to 153% higher than for adult patients with
normal weight.
Conclusion:
Patients with obesity receive higher DAPs than
normal-weight adults which may be in excess of that expected
due to their size. Therefore, radiation-related lifetime cancer
risk is increased in patients with obesity as a result of medical
radiation exposures. This indicates more dose optimisation
research is needed in this group of patients to reduce dose rate
and variation.
e:
salbeshri@hotmail.com