analytical-chemistry-2018-scientifictracks

6 / 11

Page 21
Note:
N o v e m b e r 2 1 - 2 2 , 2 0 1 8 | M a d r i d , S p a i n
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
YEARS
Analytical Chemistry 2018 Journal of Chemical Technology and Applications| Volume 2
ANALYTICAL CHEMISTRY
International Conference on
Gorgaslidze N et al., J Chem Tech App 2018, Volume 2
STUDY OF THE LIPIDS FROM THE FRUITS
OF CORYLUS AVELLANA L., GROWING IN
GEORGIA
Gorgaslidze N, Kikalishvili B, Turabelidze D,
Sulakvelidze Ts and Malania M
TSMU I. Kutateladze Institute of Pharmacochemistry, Georgia
Usual hazel-Coryllus avellana L. (Betulaceae) appropriates to high shrubby
plant is widely spread in Georgia. Fruits of the hazel is rich in lipids and
biologically active compounds: proteins, vitamins B, C, E, PP; paclitaxel, mi-
croelements. Lipids from them is used in medicine: as cholagogic, in time of
atherosclerosis, rheumatism, skin, hypertonic diseases, in oncological prac-
tice, as medical-prophylactic means.
From the fruits of Usual hazel there was derived lipids in amount 60%. Us-
ing the TLC there were established substances of following classes: hydro-
carbons, triacylglycerides, free fatty acids, sterines. There were determined
some physical-chemical constants of the crude lipids: Acid number-2-3 mg
KOH, iodine number I-100-108, index of refraction n-1,460, specific weight
d-0,943. On the following stage of the investigation with the help of meth-
od high performance liquid chromatography-HPLC were identified ten fatty
acids: dodecanic acid-0,10mg/%, tetradodecanic acid-0,10mg/%, hexadeca-
nic acid-5,1 mg/%, octadecanic acid-1,65 mg/%, 9-octadetsenic acid-80,61
mg/%, 9,12-octadecadienic acid-14,28mg/%, 9,12,15-octadecatrienic acid-
0,12mg/%, eicosanic acid-0,18mg/%, docosanic acid - 0,10mg/%, tetracosan-
ic acid-0,11mg/%. In the sum of polar lipids there were revealed five phospho-
lipids, lizophosphatidilcholin Rf-0,18, lizophosphatidilaethanolamin Rf-0, 37,
phosphatidilchocholin Rf-0, 54, phosphatidilaethanolamine Rf-0, 66, N-acyl-
phosphatidilaethanolamine Rf-0, 86. The sums neutral lipids obtained from
the fruits of hazel consist unique ratio of saturated, unsaturated and poly-
unsaturated fatty acids. In the sum neutral lipids of hazel dominates 9-octa-
detsenic and 9,12,15-octadecatrienic acids. By the pharmacologically studies
there was established that lipids from the fruits of hazel possess gastropro-
tectoric action.
Gorgaslidze N has completed her PhD at the age of 37
years from Saint-Petersburg State Chemical-Pharma-
ceutical Academy, Russia. She is a director of TSMU Iovel
Kutateladze Institute of Pharmacochemistry and profes-
sor at the department of Social and Clinical Pharmacy at
Tbilisi State Medical University. She has published more
than 100 papers in reputed journals, the author of 4 books
and 2 patens. She is a member of organizing committee
of several international conferences and meetings. She
has more 40 years of teaching experience at the Tbilisi
State Medical University, Georgia. She is founder of the
Georgian Pharmaceutical Association (President 2002-
2005) and newspaper - “Pharmacy. She is member of
scientist and young pharmacists of Georgia. Nana Gor-
gaslidze has long timework experience in the Ministry
of Health, Labor and Social Affairs of Georgia in field of
state control of quality medicinal and pharmaceutical
products and other departments of the same ministry.
BIOGRAPHY