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J Parasit Dis Diagn Ther 2017 | Volume 2 Issue 4
International Conference on
Zoology, Microbiology & Medical Parasitology
October 30-November 01, 2017 | Chicago, USA
The extended effects of
clomiphene citrate
on liver functions of mice offspring
Mohammed O Al-Jahdali and Wejdan M Henawi
King Abdulaziz University, Saudi Arabia
I
nfertility can cause considerable social, emotional and
psychological stress. Ovulatory dysfunction is one of the
most common causes of reproductive failure in sub-fertile
and infertile women. There are several approaches to
ovulation induction therapy for the management of women
with ovulatory disorders. Fertility drugs are spreading
worldwide fast and therefore many studies have reviewed
the association between the use of these drugs and
physiological, biochemical and histopathological alterations.
The aim of the present study is to evaluate the effects of
Clomiphene citrate (Clomid)® on albino mice offspring’s liver
functions. Treating mothers with CC doses 0.2 and 0.3 mg/
day caused high significant increasing in liver enzymes GPT,
GOT and ALP. In conclusion, liver disorder was clearly noticed
on the new offspring of the treated mothers with CC.
Speaker Biography
Mohammed O Al-Jahdali is the Professor of Ecological Physiology at King Abdulaziz
University, Previous Dean of Science and Art College – Rabigh campus, Saudi Arabia.
He did his PhD from the University of Alabama in 2003 and trained at Dauphin
Island Sea Lab, Dauphin Island, AL USA. His Research interest is in manipulations of
environmental parameters on physiological and ecological functions of biota at Rabigh
lagoon at the red sea, Saudi Arabia, oceanography and marine ecology, environmental
impact assessment studies, environmental pollution and pollutants, marine biology
and organisms, ecological physiology of public health and pollution-related diseases
and ecological physiology of reproduction and development
e:
moaljahdali@
kau.edu.sa