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J Clin Exp Tox 2017 Volume 1 | Issue 2
Toxicology and Pharmacology
November 01-02, 2017 | Toronto, Canada
International Conference on
K
nown as a rotten egg gas, hydrogen sulfide (H
2
S) can cause
human intoxication and death at high concentrations, which
is a major life-threatening risk for oilers or city sewage workers.
Catastrophically accumulated H
2
S gas was also responsible
for the biggest life extinction on Earth that killed 95% of all
life species on Earth, the end-Permian extinction. Research
conducted by my team as well as others over last decades
has revealed, however, the critical importance of H
2
S to the
homeostatic regulation of human health. In this talk, I will
highlight some most promising and intriguing discoveries in H
2
S
toxicology and biology, including the toxicological profile of H
2
S,
the roles of H
2
S in the regulation of blood pressure, ion channel
functions, and mitochondrial bioenergetics. H
2
S is a silent killer
whereas in the meantime we cannot live without it.
Speaker Biography
Rui Wang has completed his MD in China and PhD in Canada. He was the Vice-
President of Research of Lake Head University, Canada from 2004-2014. He has served
Laurentian University as Vice-President Research since 2015. He has published 267
peer-reviewed papers on the studies of gasotransmitters, including hydrogen sulfide
and carbon monoxide that have been cited over 20,100 times. He has also served on
the expert panel for toxicological profile for hydrogen sulfide and carbonyl sulfide for
US Department of Health and Human Services, Public Health Service, and Agency for
Toxic Substances and Disease Registry in 2013.
e:
rui.wang@laurentian.caRui Wang
Laurentian University, Canada
To live or to die – H
2
S causes the both