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N o v e m b e r 1 2 - 1 3 , 2 0 1 8 | R o m e , I t a l y
Joint Event on
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
YEARS
Surgery and Anesthesia 2018 & Euro Gastro Congress 2018 Case Reports in Surgery and Invasive Procedures| Volume 2
&
GASTROENTEROLOGY
3rd International Conference on
SURGERY AND ANESTHESIA
International Conference on
Eduardo Rubio Ruiz et al., Case Rep Surg Invasive Proced 2018, Volume 2
NEW RESOURCE FOR SHORT AND
LONG-TERM SEDATION
Eduardo Rubio Ruiz, Rafael Moguel Anchita and Ricardo Segovia
Gasque
Centro Medico de Cozumel, Mexico
Propanidido is a eugenic GABAA allosteric inhibitor at mesencephalic and
bulbar levels, that neutralizes the action of neuroleptics sites on the cen-
tral nerve system. It exhibits rapid transformation by plasma cholinesterase
into acid metabolites with no anesthetic effects. Hiltmann, on 1960-1965,
introduced it for short surgical and minor dental procedures. It has rapid on-
set of effect, analgesic effect, early onset of consciousness, initially positive
stimulant of respiratory rate, prolonged effect of muscle relaxant succinylcho-
line and rapid recovery in case of intoxication, without any venous irritation.
Purpose: To consider the cost and time benefit of general application of pro-
panidido for all endoscopic procedures.
Methods and materials: We treated 99 patients with hypnotic medication pro-
panidido and narcotic fentanyl for endoscopic procedures of multiple nation-
alities, different comorbidities, and variable ages.
Results: Shown in figures
Conclusion: It is a soft drug that causes short time of induction and rapid
metabolization, great stability, oxygen saturation over 96%, without either,
awareness, movements, ventilation depression neither accumulation titles in
blood after 25 minutes of administration. It gives the attending physician the
possibility for early onset of consciousness in 5 minutes and early 25 minutes
discharge from the hospital.
Eduardo Rubio Ruiz has medical specialty in anesthesia
from National Autonomous University of Mexico, Board
certified by the Mexican council of anesthesia, chief of
staff of anesthesia at Costamed hospital.
BIOGRAPHY