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Quratulain Fatima Masood et al., Case Rep Surg Invasive Proced 2018, Volume 2
ADIPOKINE PROFILE IN HYPERTROPHIC
BREASTS
Quratulain Fatima Masood, Q Ayub, T Perwez, T Ahmed, T Arain,
Muhammad H, Asad A, Kaleem A, Hussain I
and
Mariel Elisa
Yale University of Medicine, USA
T
he aim of the study was to reveal the pattern of adipokine production in
normal versus hypertrophic breast tissue, using protein micro arrays. The
hypothesis proposed was a differential expression of adipokines in normal
verses hypertrophic breast tissue. Twenty one surgical breast tissue samples
were taken and frozen immediately after excision. Two samples were tak-
en from normal female breasts and one from a normal male breast. Fifteen
samples frommacro mastic, and three samples from gynaecomastic breasts,
were taken during various breast reduction procedures. The proteins in the
surgical tissue samples were extracted and analyzed using protein micro ar-
rays. Protein assays from representative samples showed striking similari-
ties. The expression of protein molecules in macromastic and gyneacomastic
breasts, when compared to normal female and male representative assays,
showed similar results. Adipose tissue and capillary endothelial tissues have
an active interplay of paracrine and autocrine dynamics. Adipose tissue de-
velopment requires constant vascular remodeling and multiple angiogenic
molecules produced in adipose tissue may contribute to the complex regu-
lation of adipogenesis.
Quratulain Fatima Masood has been serving as a med-
ical intern, after graduating from Army Medical College,
national university sciences and technology. Following a
brief period at Yale as a research associate, at the de-
partment of plastics and reconstructive surgery, she be-
came the sole pioneer of the student research forum, at
her home institution. Her experience at Yale emerged as
global forum, where she mentors students at research
paper writing. Other than individual research papers, her
major completed contributions are noted at the leading
American publication groups including, encyclopedia of
global health, encyclopedia of cancer and society and En-
cyclopedia of stem cell research all published with the re-
nowned publisher SAGE publications. CPR related brain
death, options and perspectives by SM publications, is
an ongoing project an interesting perspective on deep
brain trans cranial electromagnetic stimulation, and its
application in brain dead patients. She has presented her
research across the globe, in form of posters, and oral
presentations, with the honor of having two of her pa-
pers being invited to be presented at New England hand
surgery society; at the world congress of regenerative
medicine & stem cell in China and the annual research
symposium, University of Colombo.
quratulain.fatima@gmail.comBIOGRAPHY