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Structural Biology 2018 & STD AIDS 2018 Journal of Genetics and Molecular Biology | Volume 2
S e p t e m b e r 0 3 - 0 4 , 2 0 1 8 | B a n g k o k , T h a i l a n d
alliedacademies
STD-AIDS AND INFECTIOUS DISEASES
STRUCTURAL BIOLOGY AND PROTEOMICS
&
International Conference on
International Conference on
Joint Event on
Manuel Luque Oliveros, J Genet Mol Biol 2018, Volume 2
BLOOD MIXTURE AND THE DANGER OF
DISCHARGE IN PATIENTS EXPERIENCING
HEART MEDICAL PROCEDURE WITH
EXTRACORPOREAL DISSEMINATION
Manuel Luque Oliveros
University of Sevilla, Spain
Purpose: Patients undergoing cardiac surgery with extracorporeal circulation
(ECC) frequently present haemorrhages as a complication associated with
high morbidity and mortality. One of the factors that influences this risk is
the volume of blood infused during surgery. The objective of this study was
to determine the optimal volume of autologous blood that can be processed
during cardiac surgery with ECC. We also determined the number of salvaged
red blood cells to be reinfused into the patient to minimize the risk of
haemorrhage in the postoperative period.
Methods: This was an observational retrospective cross-sectional study
performed in 162 ECC cardiac surgery patients. Data regarding the
sociodemographic profiles of the patients, their pathologies and surgical
treatments and the blood volume recovered, processed, and reinfused after
cell salvagewere alsoevaluated theoccurrenceof postoperative
haemorrhage.
Results: The volume of blood infused after cell salvage had a statistically
significant effect (p<0.01) on the risk of post-operative haemorrhage; the
receiver operating characteristic sensitivity was 0.813 and the optimal blood
volume cut-off was 1800 ml. The best clinical outcome (16.7% of patients
presenting haemorrhages) was in patients that had received less than 1800
ml of recovered and processed autologous blood, which represented a
volume of up to 580 ml reinfused red blood cells.
Conclusion: The optimum thresholds for autologous processed blood and
red blood cells reinfused into the patient were 1800 and 580 ml, respectively.
Increasing these thresholds augmented the risk of haemorrhage as an
immediate postoperative period complication.
Manuel Luque Oliveros is attached to the surgical
block of the University Hospital Virgen Macarena and
Associate Professor in the Department of Nursing,
Spain. He is Doctor by the University of Seville, with
international research awards to his credit, and more
than 200 publications in which high impact magazine
is found.
BIOGRAPHY