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Structural Biology 2018 & STD AIDS 2018
Journal of Genetics and Molecular Biology
|
Volume 2
S e p t e m b e r 0 3 - 0 4 , 2 0 1 8 | B a n g k o k , T h a i l a n d
allied
academies
STD-AIDS AND INFECTIOUS DISEASES
STRUCTURAL BIOLOGY AND PROTEOMICS
&
International Conference on
International Conference on
Joint Event on
J Genet Mol Biol 2018, Volume 2
FACTORS INFLUENCING ATTRITION AMONG PATIENTS RECEIVING
ANTI-RETROVIRAL THERAPY IN THE ACCRA REGIONAL HOSPITAL
Jerry S Sifa
Accra Regional Hospital, Ghana
Introduction:
Human immunodeficiency virus and acquired deficiency syndrome (HIV/AIDS) epidemic remains a global health
challenge. Addressing the issue of attrition is critical for ending the epidemic. We therefore sought to determine the factors
influencing attrition among patients receiving antiretroviral therapy in Accra Regional Hospital (Ridge Hospital).
Methods:
Retrospective study design was adopted using routinely collected data of National AIDS Control Programme (NACP)
on HIV/AIDS patients receiving care from 2006 to 2017 at Greater Accra Regional Hospital. Convenience sampling is used to
select the study area and unit. All gathered data was exported to STATA statistical software package for analysis including
descriptive, trend and survival analysis.
Results:
Between January 2006 and December 2017, 4,330 people living with HIV were enrolled into care. Of them, 196 (4.53%)
died and 1,166 (26.93%) were loss to follow-up (LTFU). Enrollment peaked with increased campaigns in 2008 and then fell with
expansion of treatment sites in Greater Accra region. LTFUmimicked changing enrollment; deaths peaked with shortage of ARVs
in 2015. The determinants of LTFU were: Muslims (aHR: 1.296; CI: 1.034-1.625); CD4 count <250 (aHR: 1.546; CI: 1.308-1.828);
other funding source (aHR: 0.736; CI: 0.579-0.935); completed counselling (aHR: 1.328; CI: 1.093-1.613); disclosed status (aHR:
0.798; CI: 0651-0.978). Predictors of mortality were: more than 54 years of age (aHR: 2.915; CI: 1.165-7.297); male gender (aHR:
1.507: CI: 1.051-2.160); being divorced/separated (aHR: 1.763; CI: 1.014-3.064); CD4 count <250 (aHR: 1.069; CI: 1.027-2.797);
funded by special project (aHR: 0.393: CI: 0.185-0.835).
Conclusion:
The trend of attrition was influenced by institutional and national events. Factors influencing attrition in the hospital
is comparable to those found in other parts of Africa and Asia. Interventions should therefore be implemented for optimal health.