std-aids-immunology-2019-keynote

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J Infectious Disease Med Microbiol, Volume 3

November 21-22, 2019 | Singapore

Global Experts Meeting on

International Conference on

STD-AIDS and

Infectious Diseases

Allergy, Immunology

and Rheumatology

Joint Event

allied

academies

Journal of Infectious Diseases and Medical Microbiology | Volume 3

Notes:

icroorganisms existed on this earth millions of years

beforetheevolutionofman.Beta-lactamaseproduction

is the most common mechanism of resistance in Gram

negative bacteria. They are of significant concern because

they restrict therapeutic options, cause treatment failures

and are increasing in occurrence worldwide. Amp C beta-

lactamase are Ambler class C or group I cephalosporinases

that confer resistance to cephalosporins and cephamycins and

are not affected by inhibitors (clavulanic acid, tazobactam and

sulbactam).We are seeking effective prevention and detection

of an ever- increasing range of infection by multiple drug

resistance bacteria and combating antimicrobial resiatance

including antibiotic resistance

In our study we determined the occurrence of chromosomal

and plasmid mediated β-lactamases (AmpC) gene. In

addition we evaluated the Prevalence of plasmid Amp C

beta-lactamases in E. coli and Klebsiella pneumoniae to

find its burden on Egyptian community. We compared the

performance of the phenotypic tests with polymerase chain

reaction (PCR) to reach the most convenient method of

detection without compromising accuracy and precision.

In the attempts of personalized anti-microbial therapy, we

assessed the prevalence of DHA resistant strain of beta-

lactamase resistance in Egypt and detecting its mutational

sequence.

Speaker Biography

Naiven Helmy is currently working as a Consultant of clinical microbiology

andimmunology,Researcheratclinicalandchemicalpathologydepartment,

National research center,Egypt. Member of molecular laboratory center of

excellence, National research Centre. Working in one of private megalabs

(El mokhtaber laboratory in Egypt) as clinical microbiologist. Shared in

several internationally funded community projects as Alleviating and

Managing Anemia induced Therapy for Hepatitis C Patients Title: in Seven

Villages of Egypt/ Community outreach approach for having a model of a

village controlled from diabetes with improved quality of life: Egypt. Has

13 ongoing projects dealing with genetic background of high socially –

economic burden infectious and chronic disease with many published

scientific publications in well acclaimed journals.

naivenhelmy@hotmail.com

Naiven Helmy

National Research Center, Egypt

Through personalized antimicrobial therapy, Detection and

assessing AmpC beta lactamase types in Escherichia coli and

Klebsiella pneumonia in Egyptian hospitals