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July 18-19, 2019 | Valencia, Spain
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Asian Journal of Biomedical and Pharmaceutical Sciences
ISSN: 2249-622X | Volume 9
Pharma Summit 2019
2
nd
GLOBAL PHARMA SUMMIT
SYNTHESIS CHARACTERIZATION OF 1-SUBSTITUTED BIPHENYL DERIVATIVES AS AN-
TI-OXIDANT AGENTS
Sridhar Siddiraju
Malla Reddy College of Pharmacy, India
A
series of [1, 1’-biphenyl]-4-yl)-3-substitued 2-en-1-one derivatives (4a-h) were synthesized by general
acylation methods and [1, 1’-biphenyl]-4-yl)2-oxyethyl substituted derivatives were synthesized by Frie-
dal-crafts acylation and then followed by cyclization of respective derivatives afforded targeted compounds
(5a-d). The newly synthesized derivative compounds were characterized by IR, H1NMR, 13C NMR, mass analy-
ses and screened for their
in vitro
antioxidant activity (Scavenging of hydrogen peroxide, scavenging of super-
oxide radical methods).
Sridhar Siddiraju, Asian J Biomed Pharmaceut Sci 2019, Volume 9
Sridhar Siddiraju has completed his PhD from Berhampur University, India. He is the Professor of Department of Pharmaceutical
Chemistry, Malla Reddy College of Pharmacy. He has over 35 publications in various reputed journals. He is Editorial Board Member
of reputed Journals.
drss.chem@gmail.comBIOGRAPHY