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alliedacademies
August 16-17, 2018 | Paris, France
Primary Healthcare
12th International Conference on International Conference and Medicare Expo on
&
Pediatrics Health Care
Joint Event
Journal of Current Pediatric Research | Volume: 22
Clinical profile of Paediatric HIV/AIDS
Meena Kumari Mili, Niru Prabha Saharia, Arati Deka and Swaroop Kumar Baruah
Gauhati Medical College & Hospital, India
INTRODUCTION:
Pediatric HIV/AIDS differs from adult HIV. With the availability
of antiretroviral therapy (ART), HIV infection, has now become
a chronic treatable condition in children. HIV means Human
Immunodeficiency Virus. HIV virus causes AIDS (Acquired
Immunodeficiency Syndrome) also known as SLIMdisease. AIDS
is the end stage of disease representing breakdown of immune
defense mechanism, leaving patient prey to progressive
opportunistic infections and malignancies. Infection occurs
when the virus integrates with the genetic material of a CD4
white blood cell in the immune system. Children of today are
the youth of tomorrow. HIV affects this very precious generation
and bears grave consequences to our future, our nation, the
continent and the world at large. Ever since the report of first
paediatric case in 1983, there has been an alarming increase
in the rate of disease. There is an increased frequency of
malnutrition and infections that may be more persistent,
severe and less responsive to treatment. In addition, these
growing children are left with inescapable challenges of facing
not only lifelong adherence with complex treatment regimens,
but also enormous psychosocial, mental and neuro-cognitive
issues. With the availability of antiretroviral therapy (ART),
HIV infection has now become a chronic treatable condition
in children. It is important to concentrate on paediatric HIV
as it differs from adult HIV regarding epidemiology, mode
of transmission, diagnosis, immunology, pathology clinical
spectrum, management and presentation.
AIMS & OBJECTIVES:
Study different clinical presentations of HIV/AIDS in paediatric
age group (18 months-15 years)
METHODS:
It was a hospital based observational study. The case records
of all children diagnosed with paediatric HIV infection between
1st July 2007 to 30th June 2017, who fulfill the inclusion and
exclusion criteria were reviewed and their clinical profile
prevalence were evaluated.
RESULTS:
In the study, 31 (25.84%) cases were between 18 months-3
years age, 49 (40.83%) were between >3 years – 5 years and
40 (33.33%) were of more than 5 years age. Majority of the
children were from rural area 68 (56.7%) and 52 (43.3%) were
from urban area. Perinatal (vertical) mode of transmission was
the most common mode of transmission. There were 10 (8.3%)
asymptomatic cases. Fever was the most common presenting
complaint. On clinical examination, undernutrition was the
most common finding.
In the present study, 45 cases who were on ART were followed
up at least once. Majority of the follow ups were for respiratory
problems and fever. The nutritional status and the rates of
common infection in these children on follow up were low.
CONCLUSIONS: Intensified screening of HIV infection in
asymptomatic children by high suspicion will help in diagnosing
HIV at the earliest, and thus they can be subjected to early
management helping in improving the immunological status
and thereby increase the life span of the child.
Speaker Biography
Meena Kumari Mili has done her postgraduation in Paediatrics from Gauhati Medical
College, Assam, India. She has done her research on Paediatric HIV/AIDS while she
was post graduate trainee in Gauhati Medical College, India. She has presented her
research work on paediatric HIV/AIDS in various regional and national conferences
in India and has been awarded for the same. She has also published her works on
paediatric HIV/AIDS. She has been involved in building awareness on HIV/AIDS.
e:
Notes:
Meena Kumari Mili et al., Pediatrics & Primary HealthCare 2018, Volume 22
DOI: 10.4066/0971-9032-C1-003