parkinsons-2019-scientifictracks

allied

academies

Page 23

Notes:

April 17-18, 2019 | Frankfurt, Germany

Parkinson’s, Huntington’s & Movement Disorders

International Conference on

Journal of Brain and Neurology | Volume 3

Single dose does matter: An interesting case of Parkinson’s Hyperpyrexia Syndrome

Raghavendra Bakki Sannegowda

Father Muller Medical College, India

arkinsonism - hyperpyrexia syndrome (PHS)

is a neurological emergency that mimics

neuroleptic malignant syndrome and sepsis.

Abrupt cessation of anti-Parkinson’s drugs, usually

levodopa is responsible for this syndrome. Relative

dopamine deficiency is proposed mechanism

for PHS and replacement of dopaminergic drugs

is the mainstay of treatment. We report a case

of Parkinson’s disease who presented with

manifestations of PHS after missing a single dose

of levodopa. His CPK was sent which was 3000 IUs

favouring the diagnosis of PHS with other myriad

of symptoms. Without any further delay, his anti-

PD medications were re- initiated and there was

dramatic improvement in the patient’s symptoms.

Our case is an eye opener to show that missing

even a single dose of levodopa can induce PHS,

a potentially preventable and treatable condition

which if untreated can mimic sepsis and is fatal.

Speaker Biography

Raghavendra Bakki Sannegowda is currently affiliated to Associate

Professor, Department of Neurology, Father Muller Medical College,

INDIA, continuing research in the specialized scientific area of

Neurology. He is serving as an honorary author for Journal of

Neurological Disorders & other reputed journals and has authored

several articles along with chapters in different books related to

Neurology, Neuroscience.