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O c t o b e r 1 5 - 1 6 , 2 0 1 8 | T o k y o , J a p a n
Obesity Congress 2018, Diabetes Congress 2018 & Vaccines Congress 2018
Biomedical Research
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ISSN: 0976-1683
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Volume 29
2
nd
WORLD OBESITY CONGRESS
2
nd
WORLD VACCINES AND IMMUNOLOGY CONGRESS
&
&
DIABETES AND ENDOCRINOLOGY
International Conference on
Joint Event on
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
alliedacademies.comYEARS
Biomed Res 2018, Volume 29 | DOI: 10.4066/biomedicalresearch-C5-014
USING RADIATION TO TURN THE TUMOR INTO AN “
IN SITU
” VACCINE
FOR LUNG CANCER
James Welsh
University of Texas MD Anderson, USA
F
or the last 100 years radiation has been used solely for location control, but now with the advent of immunotherapy, we have
the potential to expand the benefit of radiation to systemic disease. Our laboratory has generated the model of PD1 resistant
to lung cancer and using this model we are testing several new immunotherapies to produce abscopal systemic responses in
combination with radiation. We have recently completed three trials with 100 patients each of testing the safety and efficacy of
combing immunotherapy with radiation for lung cancer. This talk will educate the audience about the biological rationale of using
immunotherapy with antigen release from radiation along with the most up to date data on where the field is at, along with new
approaches for the future.
jwelsh@mdanderson.org