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Page 34
Insights Nutr Metab 2017
Volume 1 Issue 3
September 11-12, 2017 Edinburgh, Scotland
15 th World Congress on
Advances in Nutrition, Food Science & Technology
Nutrition World 2017
Microbiome and antioxidant system of the gut in
chicken: Food for thoughts
The microbiome of the gastrointestinal tract in poultry
is one of the major factors affecting health of birds
(especially the immune system), their productivity and
period of productive use. Furthermore, pathogens
and agents of food toxicoinfections in humans (e.g.
campylobacteriosis) may result from contamination
of eggs and meat with bacteria that are normal in
the gastrointestinal tract of poultry. There is also an
antioxidant-prooxidant balance in the gut that interacts
with microbial population and determines gut integrity
and inflammation. Our studies indicate that superoxide
dismutase and heat shock proteins are major protective
mechanisms in the gut, while mycotoxins and oxidized
fat in the diet represent negative effectors of gut health.
We find that by using vitagene-activating supplements
it is possible to improve feed conversion ratio in
growing chickens and layers due to improvement of gut
antioxidant/redox status and health. Intestinal microflora
impact on egg production and meat quality has not been
studied well using molecular genetics and genomic
techniques in relation to feed additives (e.g. probiotics,
anti-stress additives, etc.) that should be safe for human.
Neoteric metagenomic profiling of bacterial communities
using T-RFLP, RT-PCR and NGS technology provides
a powerful toolbox for monitoring intestinal microflora
at all stages of chicken development and performance.
Combined with gene expression analysis in the chicken
guts, microbiome studies can aid in understanding of
nutritional, microbiologic and genetic factors forming
poultry health and productivity, and in improving
biosafety and quality of poultry products. It seems
likely that pathogenic bacteria and prooxidants are on
one side of the balance while antioxidants, probiotics
and normoflora are on the other side of the balance
determining chicken health and their productive and
reproductive performance. Understanding this balance
is a new promising direction of the research.
Peter F Surai is supported by a grant of the Government
of Russian Federation, Contract No. 14.W03.31.0013
Biography
Peter F Surai has his expertise in animal and human nutrition and published a
number of papers as well as two books (“Natural Antioxidants inAvian Nutrition and
Reproduction”, 2002; and “Selenium in Nutrition and Health”, 2006) which became
textbooks for animal nutritionists. His recent research is devoted to the development
of effective strategies to fight commercially relevant stresses in livestock/animal
production. He successfully transferred vitagene concept from Medical Sciences
(Calabrese et al., 2007-2016) to Animal and Poultry Science and developed
stress-prevention programs based on supplying vitagene-regulating nutrients to
farm animals via drinking water. He held Honorary Professorships in Nutritional
Biochemistry at various universities in the UK, Hungary, Bulgaria and Ukraine, and
became a Foreign Member of Russian Academy of Sciences. For the last 15 years
he has been lecturing all over the world visiting more than 70 countries.
Co-Authors: Ivan I Kochish2, Darren K Griffin3, Ilya N
Nikonov4 and Michael N Romanov2,3
2Moscow State Academy of Veterinary Medicine and
Biotechnology, Russia
3University of Kent, Canterbury, UK
4BIOTROPH+ Ltd, Russia
Peter F Surai
Feed-Food Ltd, UK
Peter F Surai, Insights Nutr Metab 2017