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academies
Nov 12-13, 2018 | Paris, France
Nutraceuticals and Food Sciences
International Conference on
27
th
International Conference on
Nursing and Healthcare
&
Joint Event
Journal of Food science and Nutrition | Volume 1
Vitamin D, Diabetes and Cardiac mortality: Let the sunshine In
Karl J Neeser
Chulalongkorn University, Thailand
V
itamin D levels appeared to be lower in Obese People
and Diabetes Mellitus Type 2 Patients as today’s ongoing
research shows. Patients with Diabetes are at greater risk for
early cardiacmortality and for repeat events if they survive their
first cardiac event. Persons at risk for Diabetes or Metabolic
Syndrome have inadequate serum concentrations of Vitamin D.
Today there is great evidence relative to the impact of Vitamin D
in the development of Diabetes, Metabolic Syndrome, Diabetes
complications and the pathogenesis of Vascular Disease. Many
cellular processes are maintained by Vitamin D. Vitamin D
maintains normal resting levels of calcium and ROS in the beta
cells, acts to reduce inflammation, which is a major process
in inducing insulin resistance. When Vitamin D is deficient,
many of these processes begin to decline and this sets the
stage for the onset of diseases such as Diabetes and Vascular
Disease. Furthermore, Vitamin D also has a very significant
role in maintaining the epigenome. Epigenetic alterations are
a feature of Diabetes by which many diabetes-related genes
are inactivated by hypermethylation. Effective detection
and treatment of inadequate Vitamin D concentrations in
persons with Diabetes or those at risk for Diabetes may be
an easy and cost-effective therapy which could improve their
long-term health outcomes as well as their quality of life.
e:
karl.neeser@gmail.com