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Notes:

allied

academies

Nov 12-13, 2018 | Paris, France

Nutraceuticals and Food Sciences

International Conference on

27

th

International Conference on

Nursing and Healthcare

&

Joint Event

Journal of Food science and Nutrition | Volume 1

Vitamin D, Diabetes and Cardiac mortality: Let the sunshine In

Karl J Neeser

Chulalongkorn University, Thailand

V

itamin D levels appeared to be lower in Obese People

and Diabetes Mellitus Type 2 Patients as today’s ongoing

research shows. Patients with Diabetes are at greater risk for

early cardiacmortality and for repeat events if they survive their

first cardiac event. Persons at risk for Diabetes or Metabolic

Syndrome have inadequate serum concentrations of Vitamin D.

Today there is great evidence relative to the impact of Vitamin D

in the development of Diabetes, Metabolic Syndrome, Diabetes

complications and the pathogenesis of Vascular Disease. Many

cellular processes are maintained by Vitamin D. Vitamin D

maintains normal resting levels of calcium and ROS in the beta

cells, acts to reduce inflammation, which is a major process

in inducing insulin resistance. When Vitamin D is deficient,

many of these processes begin to decline and this sets the

stage for the onset of diseases such as Diabetes and Vascular

Disease. Furthermore, Vitamin D also has a very significant

role in maintaining the epigenome. Epigenetic alterations are

a feature of Diabetes by which many diabetes-related genes

are inactivated by hypermethylation. Effective detection

and treatment of inadequate Vitamin D concentrations in

persons with Diabetes or those at risk for Diabetes may be

an easy and cost-effective therapy which could improve their

long-term health outcomes as well as their quality of life.

e:

karl.neeser@gmail.com