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Journal of Neurology and Neurorehabilitation Research | Volume 4
November 04-05, 2019 | Melbourne, Australia
Neurology and Neurological Disorders
19
th
International Conference on
J Neurol Neurorehabil Res, Volume 4
Repetitive Transcranial Magnetic Stimulation improves Depressive symptoms and
quality of life of Poststroke patients - Prospective case series study
Hercílio Barbosa da Silva Júnior
Neuronus Institute, Brazil
Poststrokedepression(PSD)isaseriouspsychiatriccomplication
often reported after a stroke. Nearly a third of stroke survivors
experience depressive symptoms at some point, affecting their
functional recovery andquality of life. In recent years, repetitive
transcranial magnetic stimulation (rTMS) has been studied by
many researchers and found to be a safe supporting tool for
the treatment of PSD.
Objective:
We aim to evaluate the effects of rTMS on PSD and
on the quality of life of poststroke patients.
Method:
A prospective clinical case series, performed at CRER
Rehabilitation, Brazil, between June 2016 and May 2017. A
nonprobabilistic sample (n=15) was divided into 2 groups
(excitatory stimulation in F3, n=8; inhibitory stimulation in
F4, n=7) and underwent 20 sessions of rTMS. Individuals
were assessed according to the 17-item Hamilton Depression
Rating Scale (HAM-D17) and World Health Organization
Quality of Life-Brief Version (WHOQOL-BREF) questionnaire
at 3 different moments: baseline, at the end of the treatment,
and in a 1-month follow-up meeting.
Results:
Both groups presented a significant change in the
score of all WHOQOL-BREF domains and in HAM-D17. In
the group that received inhibitory stimulation (F4), score
changes were continuous and gradual, comparing the 3
moments. In the excitatory stimulated (F3) group, however,
the improvement in scores was more expressive between
baseline and the secondmoment, without significant changes
in the follow-up.
Conclusions:
The findings of this clinical study suggest that
rTMS can be a promising tool, capable of relieving depressive
symptoms and helping in the improvement of poststroke
patients’ quality of life.
Speaker Biography
HercilioBarbosadaSilvaJuniorisaPsychologist(2004)andNeuropsychologist
(2008) and he has a Master degree in Health Sciences from the Federal
University of Goiás, Brazil (2017). He worked in a huge local rehabilitation
center for almost 6 years (2011-2016), where he helped to implant the
Neuromodulation Lab in 2013. Since then he research non-invasive brain
stimulation techniques (rTMS and tDCS) in the treatment of neurological
disorders (mood, memory and language recovery after stroke or traumatic
brain injuries), psychiatric disorders (anxiety and mood disorders) and
learning disorders (ADD and ADHD). He is the founder director of the
Neuronus Institute for Trans-disciplinary Brain Studies located in Goiânia,
Goiás, Brazil, where he is based.
e:
hercilio@neuronus.com.br