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Microbiology: Current Research | Volume 3
May 20-21, 2019 | Vienna, Austria
Medical Microbiology
4
th
International Conference on
W
e have found biofilms in many chronic diseases from
eczema to psoriasis in cutaneous disease and from
arteriosclerosis to Alzheimer’s disease in internal diseases.
We have found these biofilms in extracellular and intracellular
loci and we have shown that those that are extracellular
upregulate the innate immune system. Those that are
intracellular are not exposed to the immune system. The
organisms creating these biofilms include
Staphylococci
in eczema,
Streptococci
in psoriasis,
Malassezia furfur/
ovale
in tinea versicolor,
M. leprae
in leprosy, molluscum
virus in molluscum contagiosum,
Borrelia burgdorferi
and
dental spirochetes
in Alzheimer’s disease, and others. The
locations of these biofilms are most frequently in the organ
that is involved like
Staphylococci
in the skin in eczema, but
occasionally they are found in a distant site such as the tonsils
in psoriasis and the liver, spleen and kidneys in leprosy. These
variables call for different approaches to treatment.
Speaker Biography
Herbert B Allen is a graduate of Johns Hopkins University School of
Medicine where he did his internship. He has completed his residency at
the Naval Regional Medical Center in Philadelphia, PA, USA and has served
on the boards of the American Society of Dermatology and the American
College of Physicians and has published over 40 scientific articles in the
fields of dermatology and dermatopathology. He has been the professor
and chair of the Department of Dermatology of Drexel University College
of Medicine for the past 17 years. His specialties include dermatology,
dermatopathology, skin pathology and fungal infections and is board-
certified with the American Board of Dermatology and the American Board
of Pathology.
e:
hba25@drexel.eduHerbert B Allen
Drexel University College of Medicine, USA
Microbial biofilms in chronic diseases
Herbert B Allen, Microbiol Curr Res, Volume 3
DOI: 10.4066/2591-8036-C1-004