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alliedacademies
Journal of Gastroenterology and Digestive Diseases | Volume 3
May 25-26, 2018 | New York, USA
World Liver Conference 2018
Non-alcoholic fatty liver disease (NAFLD) is one of the most
common forms of chronic liver disease which may progress
to non-alcoholic steatohepatitis (NASH). Currently there
are no therapeutic strategies for such disease. Only lifestyle
modification through diet and exercise were proven to afford
some benefit in patients with NAFLD. No pharmacologic agents
have so far been approved for the treatment of NAFLD or NASH.
Therefore, most clinical efforts have been directed at treating
the components of metabolic syndrome, namely obesity,
diabetes, hypertension and dyslipidemias. Other interventions
are directed at specific pathways potentially involved in the
pathogenesis of NAFLD, such as insulin resistance, oxidative
stress, pro-inflammatory cytokines, apoptosis, bacterial
overgrowth, and angiotensin pathway. This lecture aims to
show the potential of Tocotrienols as a promising therapeutic
option for NAFLD. This is a Systematic Review of the effects
of Tocotrienols on Non-Alcoholic Fatty Liver Disease (NAFLD).
Tocotrienols may yet prove to be an effective treatment for
Non-Alcoholic Fatty Liver Disease.
Speaker Biography
Higinio T Mappala is a full-time Medical Specialist III and Administrator at the Jose R
Reyes Memorial Medical Center, Manila, Philippines. He is a Board-certified Internist,
Gastroenterologist, Endoscopist, Clinical Nutritionist and Clinical Toxicologist. He
has served as a University Professor and Dean of two medical schools. He is a
highly-regarded Researcher, with more than 70 scientific papers, and more than 30
international publications. He is a former Board Director of the Philippine Societies of
Gastroenterology and Digestive Endoscopy, and Online Research Rater of McMaster,
Canada, and Online DynaMed Research. He has won Young Investigator’s Award at
the World Congress and Asia-Pacific Congress of Gastroenterology. He has attended
the three-level training courses on Leadership and Management by the World
Gastroenterology Organization held in Florida, USA, Dubrovnic, Croatia, Porto,
Portugal. He was nominated as one of the top 100 leading physicians 2018, Cambridge
Biographical Institute. He is a focused Lecturer on NAFLD in local and international
conventions.
e:
Higinio T Mappala
Jose R Reyes Memorial Medical Center, Philippines
The efficacy of tocotrienols in the treatment of non-alcoholic steatohepatitis: A
systematic review