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Archives of General Internal Medicine | Volume 2
&
April 04-05, 2018 | Miami, USA
International Conference on
Internal Medicine & Practice and Primary Care
International Meeting on
Breast Pathology & Cancer Diagnosis
Background & Objective:
Carcinoma of breast has become
themajor publichealthproblemamong females indeveloping
as well as developed countries. In Nepal, it comprises 6% of
total cancer cases and often diagnosed at advanced stage.
Surgical removal or modified radical mastectomy (MRM) is
the most commonly used tool for disease management. The
objective of this study is to identify the clinical, macroscopic
and microscopic features of MRM specimens.
Materials &Methods:
This prospective cross-sectional study
was carried out at Department of Pathology, Bhaktapur
Cancer Hospital, Bhaktapur, Nepal. Macroscopic and
microscopic examination provided the tumor size, stage,
grade, lymph node status, lympho-vascular invasion and
perineural invasion. Data were collected and analyzed using
SPSS 16.
Results:
The study comprised 112 breast cancer patients of
which 109 (97.3%) were females and 3 (2.7%) were males.
Invasive ductal carcinoma showed no specific type and it
was the most common type of breast carcinoma; 84 cases
accounting 75% of total cases. Carcinoma with medullary
features was secondmost common (6 cases) comprising 5.4%
cases followed by lobular, papillary, apocrine, mucinous and
NST mixed types. Grade II tumors were most frequent grade
observed in 76.79% cases followed by Grade I (12.50%) and
Grade III (10.71%).
Conclusions:
As a conclusion invasive ductal carcinoma was
the most common histological type breast cancer and the
tumors were found at T2 and N3 stage i.e. maximum at
grade II. Our study provides prognostic significance of histo-
pathological information in breast cancer management.
Speaker Biography
Rakesh Pathak has completed his MBBS from Kathmandu Medical College, Nepal
(2005) and MD Pathology from Institute of Medicine, Maharjgunj, Kathmandu,
Nepal in 2011. He got various training and observer ship from Nepal, India and South
Korea on Oncopathology. He has attended different conferences (more than 40) in
Nepal, Malaysia, India, and South Korea. He is also a Joint Secretory of Association of
Clinical Pathologist of Nepal (ACPN). Currently, he is working as Assistant Professor/
Junior Consultant at Nepal Medical College, Bhaktapur Cancer Hospital and Visiting
Consultant at Dirgayu Guru Hospital, Dr Iwamura Hospital and Nepal National Hospital.
e:
dr_rakesh@hotmail.comHistopathological evaluation of carcinoma of breast in modified radical mastectomy specimens
Rakesh Pathak
Nepal Medical College Teaching Hospital, Nepal