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Archives of General Internal Medicine | Volume 2
&
April 04-05, 2018 | Miami, USA
International Conference on
Internal Medicine & Practice and Primary Care
International Meeting on
Breast Pathology & Cancer Diagnosis
A
s breast cancer screening has evolved resulting in earlier
detection of breast cancer which is implicitly smaller in
size sohas therebeen a trend inmanagement of breast cancer
towards less invasive techniques. The FROST trial (Freezing
Instead of Resection of Small Breast Tumors) examines the
use of cryoablation therapy as an alternative to surgical
resection of primary early stage invasive breast cancer.
We briefly describe the ultrasound guided cryoablation
technique and the cryoablation algorithm used for breast
carcinoma. We describe the FROST trial study design in
detail: Primary and secondary objectives, inclusion/exclusion
criteria and follow-up strategy. Representative FROST cases
will be shared demonstrating examples of patients that have
participated in the trial and their follow-up to date (However,
no overall preliminary data will be shared at this time.) This
discussion presents the FROST trial which has been designed
to investigate cryoablation as a non-surgical minimally
invasive alternative for treating early stage invasive breast
cancer. Cryoablation is a promising therapeutic option for
treating breast carcinoma. Knowledge of the FROST trial is
important for understanding which subset of patients may
qualify for this management option in the future.
Speaker Biography
Michael J Plaza is Board Certified by the American Board of Radiology in Diagnostic
Radiology. He completed his residency in Radiology at the University of Miami/Jackson
Memorial Hospital and a fellowship in Breast Imaging at Memorial Sloan-Kettering
Cancer Center. He has multiple published peer reviewed articles and is currently
working at the Diagnostic Center for Women in Miami, FL. He is the Director of MRI
at the Diagnostic Center for Women and leads the cryoablation and clinical research
programs.
e:
mplaza@femwell.comBreast cancer cryoablation: Understanding the FROST trial
Michael J Plazam
Diagnostic Center for Women, USA