immunotherapy-2019-scientifictracks

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May 22-23, 2019 | Rome, Italy

OF EXCELLENCE

IN INTERNATIONAL

MEETINGS

YEARS

IMMUNOLOGY

AND CANCER THERAPY

Global Summit on

Immunotherapy 2019

Immunology Case Reports | Volume 3

TRAUMATIC BRAIN INJURY AS A RISK FACTOR FOR DEMENTIA: LITERATURE REVIEW

Sela Ervina-Anastasia

National and Kapodistrian University of Athens, Greece

ementia is one of the most serious complications of Traumatic Brain Injury. This disease can be mainly

caused by road accidents and falls, clearly because the effect of the force on the brain is stronger and the

changes in brain function are more radical. A retrospective cohort study which was approved by the University

of California, San Francisco and Human Research Committee and was performed from January 1, 2005, through

December 31, 2011 (follow-up, 5-7 years), found that among 51799 patients with trauma, 4361 developed

dementia compared with 6610 patients with non-TBI trauma. The correlation of traumatic brain injury and

dementia is evident especially in the larger age groups of the population. In addition, several epidemiological

studies suggest that traumatic brain injury (TBI) is a risk factor for dementia, particularly for Alzheimer’s disease

(AD), although a significant association has not always been detected. There is evidence that in mild and severe

traumatic brain injuries most patients have emerged after year’s dementia in contrast to those patients who

just had a minor injury. In conclusion, traumatic brain injury can be associated to a significant degree with the

risk of developing dementia especially to the people with increased risk. Given the high rates of TBI to the gen-

eral population serious dementia prevention measures should be taken in such incidents and clearly to carry

out more studies and even longer in order to fully understand the mechanisms that affect between traumatic

brain injury and dementia.

Sela Ervina-Anastasia, Immunol Case Rep 2019, Volume 3

Sela Ervina–Anastasia studied Νursing at the University of Western Attica, Greece and now she is a postgraduate student in the

postgraduate program of the National Kapodistrian University of Athens, Greece. Her specialization is Surgical Nursing. She has two

publications in international journals and has participated in three world medical conferences.

BIOGRAPHY