2 / 9
allied
academies
IMMUNOLOGY AND CELL BIOLOGY
BACTERIOLOGY AND INFECTIOUS DISEASES
&
Global Summit on
Global Congress on
J u n e 2 5 - 2 6 , 2 0 1 8 | A m s t e r d a m , N e t h e r l a n d s
Virology Research Journal
|
Volume 2
Page 18
Note:
Joint Event on
B
orreliosis is caused by two groups of Borrelia,
B. burgdorferi
group and
the relapsing fever Borrelia group. Until recently it was believed that
B.
burgdorferi
group is the only group that causes Lyme-like symptoms. However
we now know that relapsing fever borrelia too causes Lyme-like symptoms.
Symptoms caused by both these Borrelia groups are often confused with
MS, Chronic fatigue, osteo-arthritis, and ALS. Therefore it is necessary to
perform appropriate diagnostic tests to differentiate Borreliosis from other
diseases. Thus we have developed highly sensitive and specific immunoblots
to detect and differentiate the two groups of Borrelia. Based on our studies in
US the specificity of the imunoblots is greater 92% for IgM and 100% for IgG.
Using these immunoblots we have demonstrated that both
B.burgdorferi
and
relapsing fever Borrelia are also present. This is based on a study performed
on over 500 patients.
Biography
Jyotsna Shah has done her BSc and MSc in Bi-
ological Sciences in the UK and her PhD in diag-
nostic immunology from Nairobi University, Ken-
ya. She then joined the International Laboratory
for Research on Animal Diseases (ILRAD) as a
post-doctoral scientist where she started the first
DNA sequencing laboratory in East Africa. On
completion of her fellowship, she joined Harvard
University, Department of Tropical Medicine, as
a research fellow and continued to work on the
development of molecular tools for diagnosis of
parasitic diseases. Presently she is the President
and CEO of Igenex Inc., Palo Alto, CA, USA.
jshah@igenex.comPANEL APPROACH FOR DIAGNOSIS
OF BORRELIOSIS (LYME DISEASE
AND RELAPSING FEVER)
Jyotsna Shah
IGeneX Inc., USA
Jyotsna Shah, Virol Res J 2018, Volume 2