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Journal of Public Health Policy and Planning | Volume 3

April 08-09, 2019 | Zurich, Switzerland

Health Care and Neuroscience

International Conference on

The endocrinology of traumaƟc brain injury

William Clearfield D O

American Osteopathic Society of RheumaƟc Diseases, USA

n average, 1.7 million Americans suffer a

traumatic brain injury (TBI) yearly, resulting in

52,000 deaths, 275,000 hospitalizations, and 1.365

million ER visits. 71% of TBI victims consider their

case as ”mild,” suffering no overt injuries. Within

three months of the event, however, 56% of these

patients experience personality changes including

anxiety, depression, and other behavioral issues.

In 2012, over 400,000 vets returned from Middle

Eastern conflicts with diagnosed with Post Traumatic

Stress Disorder. Traditional therapies, including anti-

anxiety, antipsychotic and antidepressant agents,

often utilizingmultiple units of each agent, do nothing

to treat the underlying cause. A French research

team, in 1985, lead by EE Baulieu, demonstrated that

the neurosteroids pregnenolone, allopregnanolone,

progesterone, and DHEA, are produced not only in

the periphery, as orthodox medicine long believed,

but are also generated in the intracranially. A failure

of the cerebral neurosteroid mechanism leads to

erratic brain transmissions, which in turn exacerbates

mental health issues including depression, suicide,

anxiety, panic attacks, phobias, and psychosis

commonly witnessed in people living with post-

traumatic stress disorder. In this lecture, we explore

the role the neurosteroid hormones play in the face

of traumatic brain injury, the consequences of their

failure, the diagnosis of hormonal deficiencies and

insufficiencies and treatment strategies to return

the victim to a healthy premorbid hormonal state