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Hematology and Blood Disorders | Volume 2
Page 24
July 25-26, 2019 | Amsterdam, Netherlands
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
alliedacademies.comYEARS
Global Hematology 2019
4
th
International Conference on
HEMATOLOGY AND
BONE MARROW TRANSPLANTATION
PROGNOSTIC FACTORS FOR SURGICAL OUTCOME AND SURVIVAL INWOMEN TREATED
FOR BORDERLINE OVARIAN TUMORS
Mohamed Zakaria Sayer Dayer
Menoufia University, Egypt
D
ata of 92 patients diagnosed with Borderline Ovarian Tumors (BOTs) during the period from 2010 to 2017
in the National Cancer Institute (NCI), Cairo University, Egypt were retrospectively evaluated median follow
up period was 42 months. The mean age at diagnosis was 42.7 years. Histopathology was serous in 63%, mu-
cinous in 28.3% and endometrioid in 3.3%. 65 patients (70.7%) had stage 1A disease, 17 patients had stage 1B
disease (18.5%), 4 patients had stage 1C disease (4.3%), 2 patients had stage 2 disease (2.2%) and 4 patients
had stage 3 disease (4.3%) at diagnosis. 49 patients (53.3%) underwent fertility sparing surgery, of which 19
patients underwent unilateral ovarian cystectomy, 5 patients underwent bilateral ovarian cystectomy, 25 un-
derwent unilateral salpingo-oopherectomy. 43 patients (46.7%) underwent radical surgery including hyster-
ectomy, bilateral salpingo-oopherectomy. 39 patients had micropapillary disease (42%) and 2 patients had
micro invasive disease (2.2%) on histopathology. 6 patients (6.5%) had peritoneal implants of which one was
invasive and five were non-invasive. Recurrence rate in the entire study group was 18.5%, 17.6% among pa-
tients underwent radical surgery and 82.4% among patients underwent fertility sparing surgery. 12 of the re-
currences (70.6%) were borderline whereas 5 were invasive (29.4%). Stages 1A and 1B had significantly higher
disease-free survival than other stages. Patients with micro invasion had significantly lower free disease-free
survival 10.5 (9.52–11.5) vs 77.6 (70.9–84.1). Radical surgery had significantly higher FDS than fertility sparing
surgery 75.8 (70.2–81.4) vs 68.5 (58.2–78.8).
Hematol Blood Disord 2019, Volume 2