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Hematology and Blood Disorders | Volume 2

Page 24

July 25-26, 2019 | Amsterdam, Netherlands

OF EXCELLENCE

IN INTERNATIONAL

MEETINGS

alliedacademies.com

YEARS

Global Hematology 2019

4

th

International Conference on

HEMATOLOGY AND

BONE MARROW TRANSPLANTATION

PROGNOSTIC FACTORS FOR SURGICAL OUTCOME AND SURVIVAL INWOMEN TREATED

FOR BORDERLINE OVARIAN TUMORS

Mohamed Zakaria Sayer Dayer

Menoufia University, Egypt

D

ata of 92 patients diagnosed with Borderline Ovarian Tumors (BOTs) during the period from 2010 to 2017

in the National Cancer Institute (NCI), Cairo University, Egypt were retrospectively evaluated median follow

up period was 42 months. The mean age at diagnosis was 42.7 years. Histopathology was serous in 63%, mu-

cinous in 28.3% and endometrioid in 3.3%. 65 patients (70.7%) had stage 1A disease, 17 patients had stage 1B

disease (18.5%), 4 patients had stage 1C disease (4.3%), 2 patients had stage 2 disease (2.2%) and 4 patients

had stage 3 disease (4.3%) at diagnosis. 49 patients (53.3%) underwent fertility sparing surgery, of which 19

patients underwent unilateral ovarian cystectomy, 5 patients underwent bilateral ovarian cystectomy, 25 un-

derwent unilateral salpingo-oopherectomy. 43 patients (46.7%) underwent radical surgery including hyster-

ectomy, bilateral salpingo-oopherectomy. 39 patients had micropapillary disease (42%) and 2 patients had

micro invasive disease (2.2%) on histopathology. 6 patients (6.5%) had peritoneal implants of which one was

invasive and five were non-invasive. Recurrence rate in the entire study group was 18.5%, 17.6% among pa-

tients underwent radical surgery and 82.4% among patients underwent fertility sparing surgery. 12 of the re-

currences (70.6%) were borderline whereas 5 were invasive (29.4%). Stages 1A and 1B had significantly higher

disease-free survival than other stages. Patients with micro invasion had significantly lower free disease-free

survival 10.5 (9.52–11.5) vs 77.6 (70.9–84.1). Radical surgery had significantly higher FDS than fertility sparing

surgery 75.8 (70.2–81.4) vs 68.5 (58.2–78.8).

Hematol Blood Disord 2019, Volume 2