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Journal of Gastronenterology and Digestive Diseases | Volume 3
J u n e 2 5 - 2 6 , 2 0 1 8 | D u b l i n , I r e l a n d
GASTROENTEROLOGY
International Conference on
Melissa Dooley, J Gastroenterol Dig Dis 2018, Volume 3
SMALL INTESTINAL BACTERIAL
OVERGROWTH IN PATIENTS POST
MAJOR UPPER GASTROINTESTINAL
SURGERY
Melissa Dooley
GastroLife and St. James’s Hospital, Ireland
Areview of 87 patients who underwent a glucose hydrogen breath test
(HBT) for small intestinal bacterial overgrowth, following a gastrectomy
or esophagectomy, was carried out in the GI Function Unit, St. James’s
Hospital, Dublin. Exclusion criteria included complicated major upper GI
surgery and surgery performed for nonmalignant diagnoses. Statistical
analysis was performed to evaluate the association of specific factors and
the development of SIBO. Hydrogen breath tests were carried out using the
Gastro+ Gastrolyzer (Bedfont Scientific Ltd, UK). The overall rate of positive
HBT’s post-surgery was 53%. There was no significant difference in positive
HBT results according to surgery type. A subgroup of 18 patients treated with
rifaximin had follow up assessment post-surgery. Significant improvements
were reported in flatulence, borborygmic, and foul-smelling stool. Overall
impact of GI symptoms on quality of life was significantly reduced (median
score 5.39 vs 3.78, P <0.001). In our clinic, HBT is the method employed
to evaluate patients with potential SIBO owing to the procedures simplicity,
safety, and lack of invasiveness.
Melissa Dooley qualified as a Clinical Measure-
ment Scientist in 2008 obtaining a first class
honors Degree. She commenced employment
as a Gastrointestinal Physiologist in St James’s
Hospital, Dublin and began a two-year special-
ized Physiology course through De Montfort
University, Leicester. In 2016 Melissa graduat-
ed with a Master of Philosophy from the Dub-
lin Institute of Technology for her research on
Small Intestinal Bacterial Overgrowth in Post
Esophagectomy and Gastrectomy Patients.
Melissa is a fully accredited Physiologist and is
a member of both the Irish Institute of Clinical
Measurement Scientists and the British Soci-
ety of Gastroenterology. Protocols established
during her research have been implemented in
St. James’s Hospital to improve patient services
and better practices. Melissa was awarded the
RES MED/PEI award in 2008 by the Dublin Insti-
tute of Technology for her outstanding academ-
ic achievements.
BIOGRAPHY