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J Gastroenterol Dig Dis 2017 | Volume 2, Issue 3
World Gastroenterological &
Gastroenterology and Endoscopy
October 30-31, 2017 | Toronto, Canada
World Congress on
Development and validation of risk assessment tool for colorectal cancer screening in North West of
Iran
Roya Dolatkhah, Mohammad Hossein Somi, Saeed Dastgiri
and
Mohammad Asghari Jafarabadi
Tabriz University of Medical Sciences, Iran
Background&Aim:
Although the early diagnosis of colorectal
cancer reduces the associated death burden, administration
of screening programs is not a common practice even in
developed countries. Previous studies showed the lack
of national screening programs for CRC in Iran with little
information available on the screening strategies for cancer,
in general. The main aim of our study is to develop and
validate a simple, practical and efficient tool to improve CRC
risk assessment by identifying the high and moderate risk of
the disease.
Material & Methods:
We used the NCCN (National
Comprehensive Cancer Network) guidelines, because of
full details about colorectal cancer risk assessments. The
original risk assessment tool was translated from English into
Persian. The back-translation method was performed, as the
preferred method to measure. For the content validity, we
performed a scientific panel of judges, comprised 5 medical
oncologists, 3 gastroenterologists, and 2 epidemiologists.
The proportion of experts who were in agreement with item
relevance calculated as a quantitative measure of content
validity, the CVI. The questionnaires were collected and
content validity ratio (CVR) was calculated for each item. The
questionnaire was assessed for face validity by 15 individuals
to assess its acceptable and understandable for them.
Results:
The experts evaluated every item and rated them
for understandability, distinctiveness, appropriateness
to the domain of content, and relatedness to Iranian
population. Based on expert’s opinion about necessity
and completeness of each item, the acceptable CVR was
between 1 and 0.40. Afterward, CVI was calculated to be 1
to 0.70. Moreover, the means of CVR and CVI were 0.62 and
0.93 respectively for whole the questionnaire items. Changes
were made according to expert’s recommendations, and
final revised questionnaire assessed for face validity. Based
on participant’s comments, a few items needed to some
modifications and expansion.
Discussion:
The development of an executive plan to identify
the most appropriate screening method and the best age
group for screening and a specific risk assessment tool is the
main priority in Iran.
Speaker Biography
Roya Dolatkhah is an Assistant Professor of Molecular Epidemiology of Cancer and
Academic Research Assistant of Hematology and Oncology Research Center at Tabriz
University of Medical Sciences. She has graduated as MD, PhD Molecular Epidemiology
of Cancer, and active academic research staff of Hematology and Oncology Research
Center of Tabriz University of Medical Sciences with a great experience in research
and collaboration in the field of clinical cancer researches. Recently she was awarded
the IARC “50 for 50”: Empowering Future Cancer Research Leaders Fellowship. Lyon,
France-June 2016, National Distinguished Researcher Student in Iran, from Student
Research National Committee of Research & Technology Vice-Chancellor of Iran, 2013
and Gifted& Talented Students of Tabriz University of Medical Sciences
e:
royadolatkhah@yahoo.com