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Ophthalmol Case Rep 2017 Volume 1 Issue 1
August 21-23, 2017 | Toronto, Canada
EYE AND VISION
3
rd
International Conference on
S
tevens - Johnson syndrome (SJS) and toxic epidermal
necrolysis (TEN) are rare but severe and potentially
fatal mucocutaneous diseases characterized by widespread
epidermal necrosis and mucosal involvement. The two
diseases are closely related. These diseases are very
severe, with an overall mortality of 20% to 25%. Severe
ocular complications not only aggravate the severity of dry
eye syndrome, but also threaten for vision. These sight-
threatening corneal complications are the continuous
trauma caused by friction from the scarred mucosal surfaces
of the eyelids. Late ocular complications may significantly
impair the overall quality of life of these patients; those who
survive these acute diseases are often afflicted with lifelong
suffering from severe eye irritation and blindness. Supportive
treatments may be insufficient to improve the quality of
life of afflicted individuals. Scleral contact lenses are now
considered as a standard mode of treatment. They have been
reported to increase quality of life, visual acuity and ocular
comfort. The first mechanism that family of scleral contact
lenses can help is providing a fluid cushion over the cornea
by vaulting all through it, this provides an opportunity for
the cornea to heal and these family of lenses protect against
rubbing hazards of the keratinized lids and possible trichiasis
in patients suffering from severe ocular surface problems.
Autologous serum contains the vitamins, several growth
factors and fibronectin which are important for corneal and
conjunctival integrity. We investigated the efficacy and safety
of autologous serum use in a large cohort of Latin-American
patients with SJS and TEN 1-3 Sotozono Scale fitted with ScCL
designed with the aim of the OCT Visante.
Speaker Biography
Enoc Sandoval has received his degree in Optometry from the National Autonomous
University of Mexico. He has lectures and workshops on the treatment of Ocular
Surface Disease with Scleral Devices and Specialized Contact Lenses. He has a degree
in Histopathology, and has done research in the field of Histopathology of Keratoconus,
Eye Care Provider for the International Stevens-Johnson Syndrome Foundation and
International Xcel Specialty Contacts Consultant. He has worked at the Association to
Avoid Blindness in Mexico (laboratory of Ocular Pathology), at the National Institute
of Psychiatry “Ramón de La Fuente Muñíz” (Psychoneuroimmunology Laboratory),
in The Hospital Angeles del Pedregal (Laboratory of Pathology) and currently he is
practicing his private practice at the Hospital Angele’s Ophthalmological Sciences
Institute focusing his efforts in the area of specialty contact lenses for keratoconus as
well as other degenerations and corneal ectasias, patients with post-refractive surgery
complications as well as Ocular Surface Disease.
e:
admin@oftalmologiadelpedregal.comGas-permeable scleral contact lens OCT designed-20% autologus serum as therapy for visual
rehabilitation and management of chronic ocular surface disease attributable to TEN and SJS.
Cesar Enoc Sandoval Perez
Ophthalmological Science Institute, Mexico