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Ophthalmol Case Rep 2017 Volume 1 Issue 1

August 21-23, 2017 | Toronto, Canada

EYE AND VISION

International Conference on

Statement of the Problem:

Topical steroids are known to

increase intraocular pressure (IOP). The purpose of this

study is to analyze the effect of anti-inflammatory drops

(i.e. comparing topical corticosteroids versus non-steroidal

anti-inflammatory drugs - NSAIDs) on intraocular pressure

following Selective Laser Trabeculoplasty (SLT).

Methodology & Theoretical Orientation:

37 consecutive

patients with open-angle glaucoma were randomly allocated

into 2 treatment groups after a SLT procedure: ketorolac

0.5% (Acular®, N = 19) and fluorometholone 0.1% drops

(FML®, N =18). IOP was measured 1h, 24h, 1 week, and 1, 3

and 6 months after SLT.

Findings:

IOP reduction was significant in both groups (mean

reduction 5.22 ± 3.55 mmHg in the ketorolac group, and 5.19

± 3.57mmHg in the fluorometholone group,

< 0.001). There

were no statistically significant differences in IOP between

both groups through follow-up, except significantly lower

IOP in the ketorolac group at 3 months (18.14 ± 2.49 mmHg)

than in the fluorometholone group (20.88 ± 3.24 mmHg,

p = 0.009), with no differences at 6-month follow-up (mean

IOP in both groups 19.09 ± 3.08 mmHg, and 19.69 ± 2.85

mmHg, respectively,

= 0.575). There were no statistically

significant differences in mean IOP in the first 24 hours

following the procedure (22.26 ± 4.73 in the ketorolac group

and 24.36 ± 5.76 mmHg in the fluorometholone group,

= 0.236).

Conclusion & Significance:

The anti-inflammatory treatment

after SLT does not seem to have a short-term effect on the

ocular hypotensive efficacy of selective laser trabeculoplasty,

nor on the incidence of hypertensive peaks in the early post-

treatment follow-up.

Speaker Biography

Laura Palmero Fernandez is an Ophthalmologist based in Madrid, Spain. She currently

combines her work at King Juan Carlos University Hospital with a private practice. Her

subfield of expertise includes cornea and ocular surface diseases, and cataract and

refractive surgery. Her research is focused on keratoplasty techniques, keratoconus

and challenging cornea cases.

laurapalmerof@gmail.com

Effect of Anti-inflammatory treatment on intraocular pressure after selective laser trabeculoplasty

Laura Palmero Fernandez

Hospital Clinico San Carlos, Spain