euro-gastroenterology-clinical-pharmacy-2019-keynote

5 / 5

Euro Gastroenterology 2019 & Clinical Pharmacy 2019 Archives of General Internal Medicine | ISSN: 2591-7951 | Volume 3
Page 45
March 25-26, 2019 | Amsterdam, Netherlands
&
GASTROENTEROLOGY AND HEPATOLOGY
4th International Conference on
CLINICAL PHARMACY & PHARMACY PRACTICE
9th World Congress on
Joint Event on
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
YEARS
THE EFFICACY OF URSODEOXYCHO-
LIC ACID IN THE TREATMENT OF
NON-ALCOHOLIC STEATOHEPATITIS:
A 10-YEAR SYSTEMATIC REVIEW
Non-Alcoholic Fatty Liver Disease (NAFLD) is one of the most common
forms of chronic liver disease which may progress to nNon-Alcoholic
Steatohepatitis (NASH). Currently there are no therapeutic strategies for
such disease. Only lifestyle modification through diet and exercise were
proven to afford some benefit in patients with NAFLD. No pharmacologic
agents have so far been approved for the treatment of NAFLD or NASH.
Therefore, most clinical efforts have been directed at treating the com-
ponents of metabolic syndrome, namely obesity, diabetes, hypertension
and dyslipidemias. Other interventions are directed at specific pathways
potentially involved in the pathogenesis of NAFLD, such as insulin resis-
tance, oxidative stress, pro-inflammatory cytokines, apoptosis, bacterial
overgrowth, and angiotensin pathway.
This lecture aims to show the potential of Ursodeoxycholic Acid (UDCA)
as a promising therapeutic option for NAFLD. This is a 10-year Systematic
Review of randomized controlled trials on the effects of Ursodeoxycholic
Acid on Non-Alcoholic Fatty Liver Disease. (NAFLD).
Ursodeoxycholic Acidmay yet prove to be a therapeutic option for Non-Al-
coholic Fatty Liver Disease.
Higinio T Mappala, Arch Gen Intern Med 2019, Volume 3
DOI: 10.4066/2591-7951-C1-022
Higinio T Mappala is a distinguished physi-
cian and medical researcher with 30 years of
clinical experience, as well as a prolific com-
municator and lecturer in both academic and
clinical fora. He is a board-certified specialist
in internal medicine with board-certified
subspecialties in gastroenterology, endos-
copy, clinical toxicology and pharmacology,
and clinical nutrition. He is university profes-
sor, a dean of the School of Medicine, and ad-
ministrator at the undergraduate, graduate,
and postgraduate levels; an author of more
than 50 scientific papers. As a prolific lectur-
er, he has been a focused lecturer on NAFLD
for more than 10 years.
Higinio T Mappala
Jose Reyes Memorial Medical Center, Philippines
BIOGRAPHY