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Journal of Clinical and Experimental Toxicology | Volume: 3

February 21-22, 2019 | Paris, France

Environmental Toxicology and Pharmacology

International Conference on

T

he impact of deltamethrin on the freshwater fish

Heteropneustes fossilis

exposed to two sub lethal

concentrations (0.09 mg/L and 0.18 mg/L) for 30 days on the

activities of endocrine glands viz. prolactin gland, corpuscles

of stannous and ultimobranchial gland. Changes in the

structure of endocrine gland lead significant variation in

inorganic ions concentration Na

+

, K

+

, Ca2

+

and Mg2

+

in brain,

kidney, gills and intestine of

H. fossilis

. Ca2

+

/ Mg2

+

ATPase

activities significantly decreased in all vital tissues viz.,

brain, gills, intestine and kidney at both the exposure for 30

days in

H. fossilis

. The ultimobranchial gland exhibited mild

histological changes at lower concentration of deltamethrin.

At higher concentration decrease in staining response of the

cytoplasm, decrease in nuclear volume and degeneration

in the cells were noticed. In corpuscle of stannous sever

changes observed with increase in granulation, vacuolation

and degeneration of cell membrane noticed at higher

concentration of deltamethrin. In prolactin cells sever

changes observed at both the concentration for 30 days

exposure. Significant changes observed in ionic balance

in vital tissues brain > gill> intestine > kidney of the fish

exposed to higher concentration of deltamethrin. Significant

changes noticed in the vital organs viz. Ionic levels in brain,

gills, kidney and intestine. During exposure of deltamethrin

endocrine glands, brain and intestine found to be most

affected tissues of the fish.

Speaker Biography

Prem Singh Bugasara is working as an associate professor, department of Zoology, Shri

Baldev Ram Mirdha Government College, Nagaur, Rajasthan. He has been associated

with profession for 16 years. He was awarded Ph.D degree from Maharaja Ganga Singh

University, Bikaner for research work on blackbucks. He is passionately engaged in

biodiversity conservation and has conducted several seminars and awareness programs

to encourage people to protect native flora and fauna. He always tries to improve society

and youth by discussing various social issues. He has completed a research project on

Wildlife conservation and assessment of biodiversity in Rotu Conservation Reserve, Nagaur

(Rajasthan)in year 2016-17 and is continuing with another wildlife research project. He has

published research papers on various topics in national and international journal.

e:

prembugasara@gmail.com

Prem Singh Bugasara

SBRM

Govt.PG

College, India

Deltamethrin induced changes in endocrine glands regulating calcium and

ionic balance in

Heteropneustes fossilis

Notes:

Prem Singh Bugasara, J Clin Exp Tox, Volume 3

DOI: 10.4066/2630-4570-C1-004