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Page 49

Joint Event

November 29-30, 2019 | Frankfurt, Germany

28

th

International Conference on

3

rd

International Conference on

Diabetes and Endocrinology

Diabetes and Metabolism

&

2

0

1

9

CONGRESS

DIABETES

2019

DIABETES

Journal of Diabetology | Volume 3

ZnO Nanostructure based Electrochemical Bio-Sensors for intra/extracellular glucose

measurement

Muhammad. H Asif

Lund University, Sweden

T

he nanostructure of zinc oxide (ZnO) such as nanorods

and nanowires has interesting nanosurfaces compare

to its bulk properties. Recently ZnO have attracted much

interest because of its semiconducting, electrochemical,

catalytic properties, being biosafe and biocompatible

morphology combined with the easiness of growth.

This implies that ZnO has a wide range of applications in

optoelectronics, sensors, transducers, energy conversion

and medical sciences. This abstract relates specifically to

electrochemical glucose biosensors for extra/intracellular

environment based on functionalized zinc oxide nanorods

for biochemical applications. To adjust the sensor for

intracellular measurements, the ZnO nanorods were grown

on the tip of a borosilicate glass capillary (0.7μm in diameter)

and functionalized with polymeric membrane or enzymes

for intracellular selective glucose sensors. The sensor in

this study was used to detect and monitor real changes of

glucose across human fat cells and frog cells using changes

in the electrochemical potential at the interface in the

intracellular microenvironment. The fabrication of such type

of device aims to explain the methodology of ions/glucose

sensing using functionalized ZnO nanorods for intracellular

environment. This nanoelectrode device paves the way to

enable analytical measurements in single living cells.

e

:

muhammad.asif@ftf.lth.se