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Journal of Diabetology | Volume 3
Page 16
July 25-26, 2019 | Amsterdam, Netherlands
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
YEARS
Diabetes Conference 2019
3rd International Conference on
DIABETES, NUTRITION,
METABOLISM & MEDICARE
BLOOD PRESSURE AND HEART RATE VARIABILITY OF RECENT AND LONG STANDING
DIABETES
Ana Leonor Rivera, B Estañol, R Fossion and A Frank
Universidad Nacional Autónoma de México (UNAM), USA
C ardiovascular variability (blood pressure and heart rate) is affected by Diabetes Mellitus (DM). To study this
effect, simultaneous non-invasive records of interbeat intervals (IBI) and beat-to-beat systolic blood pres-
sure (SBP) variability of patients during supine, standing and controlled breathing tests were analyzed for re-
cently diagnosed and long-standing DM patients comparing the results for 30 rigorously screened healthy sub-
jects (Control). The most relevant changes as diabetes evolves are the loss of the cardio-respiratory modulation,
standard deviation of the IBI detrended signal diminishes (Heart rate signal becomes more“rigid”) while for SBP
increases, skewness for IBI approaches zero (Signal fluctuations gain symmetry), while for SBP becomes asym-
metric and kurtosis increases (Fluctuations concentrate around the median). This may be due to a progressive
decrease of parasympathetic and sympathetic activity to the heart and blood vessels as diabetes evolves.
Ana Leonor Rivera et al., J Diabetol 2019, Volume 3
Ana Leonor Rivera has completed her PhD from Universidad Nacional Autónoma de México (UNAM). She works at UNAM as re-
searcher on Complex Systems. She has 50 publications that have been cited over 500 times and her publication H-index is 12. She is
interested on blood pressure and heart rate variability.
BIOGRAPHY