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Journal of Neurology and Neurorehabilitation Research | Volume: 3
August 16-17, 2018 | Copenhagen, Denmark
Dementia and Alzheimer ’s Disease
10th World congress on
The recent achievements in the studies of neuroplasticity
led an enhanced attention to internal restorative strategies.
Neurorehabilitation, based on the principles of neuroplasticity,
is considered to be the promising way to mitigate the adverse
consequences of traumatic brain injury (TBI) to cognitive
functions. The ability of the brain to restore and to create the
neural connections makes it essential to search for methods
that could stimulate the restoration of disturbed networks and
also can help building the newways to compensate the deficit of
the cognitive functions. Technologies of cognitive rehabilitation
relying on the structural and functional plasticity of the brain
include programs of mental and physical training and various
techniques of stimulation therapy, including transcranial
magnetic and electrical stimulation, and noninvasive sensory
stimulation exploiting the BWE phenomenon. Currently, the
stimulation therapy applies a periodic rhythm of audio, visual
and other signals which can provide the local improvement of
the cortical activity in the particular range of oscillations. But it
is unable to restore the complex dynamics of the activity of the
brain characteristic of a healthy person and therefore, cognitive
performance of the person. We suppose that in patients after
brain injuries, the fractal flicker stimulation, and the stimulation
by complex-structured sound tones and signals of other
modalities will promote activating the structural-functional
plasticity and improving the memory and other cognitive
functions. Changes in the cortical activity evoked by fractal
stimuli can mediate the impact of stimulation on cognitive
performance. Theuseof newapproaches toneurorehabilitation
aimed to increase the potential of neuroplasticity can also
improve the therapeutic effects of other known methods of the
training the brain. That is, the period of enhanced plasticity can
present some therapeutic temporal window, during which an
increase in the efficiency of different others neurorehabilitation
measures should be expected.
Speaker Biography
Marina Zueva is a professor of Pathophysiology and graduated from the Lomonosov
Moscow State University (Physiology of Higher Nervous Activity), received her Ph.D.
and Biol. Sci. D. from Moscow Helmholtz Research Institute of Eye Diseases. Currently,
she is the Head of the Division of Clinical Physiology of Vision at the Moscow Helmholtz
Research Institute of Eye Diseases. She has published over fifteen peer-reviewed
full-length papers in English (over 100 in Russian) and presented near 70 topics at
international conferences.
e:
Marina Zueva
Moscow Helmholtz Research Institute of Eye Diseases, Russia
Stimulation therapy with complex-structured stimuli in the neurorehabilitation after TBI