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Journal of Neurology and Neurorehabilitation Research | Volume 3
allied
academies
Nov12-13, 2018 | Paris, France
Central Nervous System & Therapeutics
International Conference on
Background and Purpose: To assess the role of magnetic
resonance venography (MRV) for detecting transverse sinus
stenosis and the importance of this finding in idiopathic
intracranial hypertension (IIH), and to propose an index that
contributes to this diagnosis.
Materials and Methods: We retrospectively assessed
consecutive intracranial MRV of patients aged >18 years
diagnosed with IIH according to the diagnostic criteria,
between January 2010 and July 2012. The assessments were
randomly analyzed by 3 radiologists. Stenosis in the right and
left transverse sinuses were independently classified according
to the following scale: 0, normal; 1, stenosis <33%; 2, stenosis
33–66%; 3, stenosis >66%; and 4, hypoplasia or agenesis. We
establishedan indexbasedonmultiplicationof thestenosis scale
values for each transverse sinus. A point and range estimate of
sensitivity, specificity, and the area under the receiver operating
characteristic curve was performed to obtain cut-off points to
differentiate the controls and patients.
Results: Sixty-three individuals were included in this study: 32
(50.8%; 31 [96.9%] women and 1 [3.1%] man) diagnosed with
IIH and 31 (49.2%) controls. For all examiners, the IIH group
showed a higher degree of stenosis than the control group.
Index values ≥4 for IIH diagnosis had a sensitivity and specificity
of 94.7% and 93.5%, respectively.
Conclusion: MRV should be used to assess patients with
suspected IIH, and bilateral transverse sinus stenosis should
be considered for the diagnosis. The stenosis-classifying index
proposed in this study is a fast and accessible method for
diagnosing IIH.
Speaker Biography
Gustavo Balthazar Da Silveira Carvalho is a radiologist specialized in neuroradiology and
has completed his PhD at the age of 37 years from Federal University of Sao Paulo, Brazil.
He is the medical director of RBD Imagem, a private public partnership with the State
Government of Bahia (Brazil) to provide high quality diagnostic imaging service in 11 public
hospitals, including a residency program in diagnostic imaging.
e:
Gustavo Balthazar Da Silveira Carvalho
Federal University of Sao Paulo, Brazil
A new index for the assessment of Transverse Sinus Stenosis for the diagnosis of
Idiopathic Intracranial Hypertension